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PPP1R10 抗体 (AA 151-250)

PPP1R10 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1386277
发货至: 中国
  • 抗原 See all PPP1R10 抗体
    PPP1R10 (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 10 (PPP1R10))
    抗原表位
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 151-250
    适用
    • 11
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 10
    • 1
    克隆类型
    • 10
    • 1
    多克隆
    标记
    • 11
    This PPP1R10 antibody is un-conjugated
    应用范围
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    人, 小鼠, 大鼠
    预测反应
    Dog,Cow,Sheep,Pig
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human PNUTS/PPP1R10
    亚型
    IgG
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    PPP1R10 (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 10 (PPP1R10))
    别名
    PNUTS/PPP1R10 (PPP1R10 产品)
    别名
    CAT53 antibody, FB19 antibody, PNUTS antibody, PP1R10 antibody, R111 antibody, p99 antibody, Fb19 antibody, Pnuts antibody, 2610025H06Rik antibody, Cat53 antibody, D17Ertd808e antibody, CHUNP6885 antibody, fe15d12 antibody, fk54b08 antibody, ppp1r10l antibody, wu:fe15d12 antibody, wu:fk54b08 antibody, protein phosphatase 1 regulatory subunit 10 antibody, protein phosphatase 1, regulatory subunit 10 antibody, protein phosphatase 1 regulatory subunit 10 S homeolog antibody, PPP1R10 antibody, Ppp1r10 antibody, ppp1r10.S antibody, ppp1r10 antibody
    背景

    Synonyms: CAT 53, CAT53, FB 19, FB19, FB19 protein, MHC class I region proline rich protein CAT53, p99, Phosphatase 1 nuclear targeting subunit, Phosphatase nuclear targeting subunit, PNUTS, PP1 binding protein of 114 kDa, PP1R10, Protein phosphatase 1 regulatory inhibitor subunit 10, Protein phosphatase 1 regulatory subunit 10, Serine/threonine protein phosphatase 1 regulatory subunit 10, PP1RA_HUMAN.

    Background: Eukaryotic protein phosphorylation and dephosphorylation on serine and threonine residues regulates numerous cell functions, including division, homeostasis and apoptosis. A group of proteins that play a major role in this process are the serine/threonine protein phosphatases. Protein phosphatase (PP) holoenzyme is a trimeric complex that contains a regulatory subunit, a variable subunit and a catalytic subunit. Families of PP catalytic subunits include PP1, PP2A, PP2B, PP2C, PPX and PP5. Regulatory subunits include nuclear inhibitor of PP1 (NIPP1), PP1 nuclear targeting subunit (PNUTS), PP2A-A, PP2A-B, PP2A-B56, PP2A-C, PP2B-B and PR48. PNUTS, also designated CAT53 or FB19, is encoded by the gene PPP1R10. PNUTS acts as an inhibitor for the phosphatase activity of PP1 Alpha and PP1 Gamma. It is a nuclear protein primarily detected in nucleoplasmic bodies and within nucleoli. PNUTS expression levels are highest in brain, heart, lung, placenta, liver, kidney, pancreas and skeletal muscle.

    途径
    Protein targeting to Nucleus
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