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SGK1 抗体

This anti-SGK1 antibody is a 兔 多克隆 antibody detecting SGK1 in WB, IHC (p) 和 IF (p). Suitable for 人, 小鼠, 大鼠, Cow 和 犬.
产品编号 ABIN1385850
发货至: 中国

Quick Overview for SGK1 抗体 (ABIN1385850)

抗原

See all SGK1 抗体
SGK1 (serum/glucocorticoid Regulated Kinase 1 (SGK1))

适用

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人, 小鼠, 大鼠, Cow, 犬

宿主

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克隆类型

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多克隆

标记

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This SGK1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 交叉反应

    Cow, 犬, 人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human SGK1

    亚型

    IgG
  • 应用备注

    WB(1:100-500)
    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    SGK1 (serum/glucocorticoid Regulated Kinase 1 (SGK1))

    别名

    SGK1

    背景

    Synonyms: Serum/glucocorticoid regulated kinase 1, SGK 1, SGK-1, Serine/threonine protein kinase SGK, Serine/threonine protein kinase Sgk1, Serum and glucocorticoid regulated kinase, Serum/glucocorticoid regulated kinase, SGK 1, SGK.

    Background: SGK1 is a protein kinase that plays an important role in cellular stress response. SGK1 activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. Sustained high levels of SGK1 and activity may contribute to conditions such as hypertension and diabetic nephropathy. This protein also mediates cell survival signals, as it has been shown to phosphorylate and negatively regulate the pro apoptotic FOXO3A protein. Ser 422 is a critical site on the protein and may be involved in its activation.

    分子量

    49kDa

    途径

    MAPK Pathway, Notch Signaling, Steroid Hormone Mediated Signaling Pathway
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