Herpes Simplex Virus Type 1 (HSV1) 抗体
-
- 抗原
- Herpes Simplex Virus Type 1 (HSV1)
- 适用
- Herpes Simplex Virus (HSV)
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- 非结合性
-
应用范围
- ELISA, Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- Virus
- 交叉反应 (详细)
- Herpes simplex virus 1
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from Herpes simplex virus 1 Neurovirulence factor ICP34.5
- 亚型
- IgG
-
-
- 应用备注
-
WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200 - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
-
- 抗原
- Herpes Simplex Virus Type 1 (HSV1)
- 别名
- HSV 1
- 物质类
- Virus
- 背景
-
Synonyms: Herpes simplex virus 1, Herpes Simplex Virus, Herpes Simplex Virus Type 1, HSV 1, Human herpesvirus 1, Human herpesvirus type 1,ICP34_HHV1F, Infected cell protein 34.5, Neurovirulence factor ICP34.5, protein gamma(1)34.5, RL1
Background: Contributes to HSV resistance to the antiviral effects of alpha/beta interferon. Recruits the serine/threonine-protein phosphatase PPP1CA/PP1-alpha to dephosphorylate the translation initiation factor eIF-2A, thereby counteracting the host shutoff of protein synthesis involving double-stranded RNA-dependent protein kinase EIF2AK2/PKR. Also down-modulates the host MHC class II proteins cell surface expression. Acts as a neurovirulence factor that has a profound effect on the growth of the virus in central nervous system tissue, probably through its ability to maintain an environment favorable for viral replication.
- UniProt
- P08353
-