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c-MET 抗体

MET 适用: 人 FACS, cELISA 宿主: 大鼠 Monoclonal BCI-3E7 unconjugated
产品编号 ABIN1381745
发货至: 中国
  • 抗原 See all c-MET (MET) 抗体
    c-MET (MET) (Met Proto-Oncogene (MET))
    适用
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    大鼠
    克隆类型
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    单克隆
    标记
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    This c-MET antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS), Cell-ELISA (cELISA)
    特异性
    Anti-human c-Met
    产品特性
    Selection: Based on recognition of the complete native protein expressed on transfected mammalian cells
    纯化方法
    Protein G
    免疫原
    genetic immunisation with cDNA encoding human c-Met
    克隆位点
    BCI-3E7
    亚型
    IgG2b kappa
    Top Product
    Discover our top product MET Primary Antibody
  • 应用备注
    Flow cytometry: 1.2 µg/10^6 cells
    CELISA: 1:200 - 1:400
    For each application a titration should be performed to determine the optimal concentration.
    限制
    仅限研究用
  • 缓冲液
    PBS, pH 7.2
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C
    储存方法
    short term: 2 °C - 8 °C, long term: -20 °C
  • 抗原
    c-MET (MET) (Met Proto-Oncogene (MET))
    别名
    c-Met (MET 产品)
    别名
    AUTS9 antibody, HGFR antibody, RCCP2 antibody, c-Met antibody, AI838057 antibody, HGF antibody, Par4 antibody, Hgfr antibody, c-met antibody, MET antibody, C-MET antibody, met antibody, met-A antibody, MET proto-oncogene, receptor tyrosine kinase antibody, met proto-oncogene antibody, MET proto-oncogene, receptor tyrosine kinase L homeolog antibody, MET antibody, Met antibody, met.L antibody
    背景
    C-MET is a receptor tyrosine kinase that is activated upon Hepatocyte Growth Factor (HGF) binding. c-MET is produced as a single-chain precursor and plays en essential role in embryonic development and wound healing. It belongs to the class of Single-pass type I membrane proteins and it is normally expressed by cells of epithelial origin while the expression of HGF is restricted to cells of mesenchymal origin in an almost perfect paracrine paradigm. Overexpression of c-MET can be found in several kinds of tumor progression.
    UniProt
    P08581
    途径
    RTK signaling, Carbohydrate Homeostasis, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor
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