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FAS 抗体 (Biotin)

FAS 适用: 人 FACS 宿主: 小鼠 Monoclonal DX2 Biotin
产品编号 ABIN135815
发货至: 中国
  • 抗原 See all FAS 抗体
    FAS (TNF Receptor Superfamily, Member 6 (FAS))
    适用
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    小鼠
    克隆类型
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    单克隆
    标记
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    This FAS antibody is conjugated to Biotin
    应用范围
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    Flow Cytometry (FACS)
    特异性
    Human/Rhesus/African Green Monkey/Sooty Mangabey CD95, Mr 45 kDa
    产品特性
    Mouse Anti-Human CD95-BIOT
    免疫原
    Human CD95 transfected L cells
    克隆位点
    DX2
    亚型
    IgG1
    Top Product
    Discover our top product FAS Primary Antibody
  • 应用备注
    • Applications: FC - Quality tested , IHC-FS - Reported in literature , IHC-PS - Reported in literature , ICC - Reported in literature , IP - Reported in literature , ELISA - Reported in literature , Apop - Reported in literature
    • Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells FITC, BIOT, PE, APC, AF488 and AF647 conjugates 10 L/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
    说明

    in vivo induction of apoptosis

    限制
    仅限研究用
  • 缓冲液
    100 tests in 1.0 mL of PBS/Sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect conjugated products from light.
    Each reagent is stable for the period shown on the bottle label if stored as directed.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C
  • 抗原
    FAS (TNF Receptor Superfamily, Member 6 (FAS))
    别名
    CD95 (FAS 产品)
    别名
    ALPS1A antibody, APO-1 antibody, APT1 antibody, CD95 antibody, FAS1 antibody, FASTM antibody, TNFRSF6 antibody, AI196731 antibody, APO1 antibody, TNFR6 antibody, Tnfrsf6 antibody, lpr antibody, Fas cell surface death receptor antibody, Fas (TNF receptor superfamily member 6) antibody, FAS antibody, Fas antibody, fas antibody
    背景
    CD95, also known as Fas and Apo-1, is a 40-50 kDa type I transmembrane glycoprotein and a member of the tumor necrosis factor receptor superfamily. It is expressed by activated lymphocytes, monocytes, neutrophils, fibroblasts and cell lines. Fas ligand binding to CD95 induces apoptosis in activated mature lymphocytes thereby playing a role in maintaining peripheral tolerance. Crosslinking of CD95 by the monoclonal antibodies DX2 and DX3 delivers an apoptotic signal to Fas-sensitive cells, indicating that these monoclonal antibodies recognize a functional epitope of CD95.
    途径
    p53 Pathway, Apoptosis, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
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