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CD51 抗体 (PE)

ITGAV 适用: 人 IHC, FACS 宿主: 小鼠 Monoclonal 13C2 PE
产品编号 ABIN135793
发货至: 中国
  • 抗原 See all CD51 (ITGAV) 抗体
    CD51 (ITGAV) (Integrin alpha V (ITGAV))
    适用
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    宿主
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    小鼠
    克隆类型
    • 57
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    单克隆
    标记
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    This CD51 antibody is conjugated to PE
    应用范围
    • 50
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    Immunohistochemistry (IHC), Flow Cytometry (FACS)
    特异性
    Human/African Green Monkey/Rabbit/Bovine CD51, Mr 125 & 24 kDa
    产品特性
    Mouse Anti-Human CD51-PE
    免疫原
    Cell suspension containing osteoclasts from osteoclastomas
    克隆位点
    13C2
    亚型
    IgG1
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  • 应用备注
    Working Dilution:
    FACS: 10 µL/10^6 cells
    Representative data are included in this product insert.

    Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
    限制
    仅限研究用
  • 缓冲液
    Product is supplied as 100 tests in 1.0 mL of PBS / NaN3 and a stabilizing agent.
    注意事项
    Do not freeze!
    Protect conjugated products from light.

    Each reagent is stable for the period shown on the bottle label if stored as directed.
    储存条件
    4 °C
  • 抗原
    CD51 (ITGAV) (Integrin alpha V (ITGAV))
    别名
    CD51 (ITGAV 产品)
    别名
    1110004F14Rik antibody, 2610028E01Rik antibody, CD51 antibody, D430040G12Rik antibody, MSK8 antibody, VNRA antibody, VTNR antibody, Cd51 antibody, integrin subunit alpha V antibody, integrin alpha V antibody, ITGAV antibody, Itgav antibody
    背景
    CD51 represents the 150 kDa integrin V chain that associates with integrin 3 (CD61) to form the CD51/CD61 vitronectin receptor on endothelial cells, certain activated leukocytes, NK cells, macrophages, neutrophils and platelets. CD51 is the most promiscuous integrin a subunit, it can form heterodimers with the 1 (CD29), 3 (CD61), 5, 6 and 8 subunits in various tissues. CD51/CD61 acts as an activation-independent receptor for platelet attachment and spreading on vitronectin and other RGD-containing proteins, including matrix components. It also mediates leukocyte-endothelial cell adhesion via interaction with CD31.
    途径
    Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex
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