Histone 3 抗体 (AA 26-30)
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北京 101111
Quick Overview for Histone 3 抗体 (AA 26-30) (ABIN1355846)
抗原
See all Histone 3 (H3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 26-30
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特异性
- The antibody detects endogenous level of total Histone H3 protein.
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免疫原
- Peptide sequence around AA 26-30 (A-R-K-S-A) derived from Human Histone H3. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
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应用备注
- Western blotting: 1:500-1:1000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C
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: "Paeoniflorin reduced BLP-induced inflammatory response by inhibiting the NF-?B signal transduction in pathway THP-1 cells." in: Central-European journal of immunology / Polish Society for Immunology and eleven other Central-European immunological societies, Vol. 39, Issue 4, pp. 461-7, (2015) (PubMed).
: "Protective effects of Salvianolic acid B on Schwann cells apoptosis induced by high glucose." in: Neurochemical research, Vol. 37, Issue 5, pp. 996-1010, (2012) (PubMed).
: "Inhibitory effects of salvianolic acid B on apoptosis of Schwann cells and its mechanism induced by intermittent high glucose." in: Life sciences, Vol. 90, Issue 3-4, pp. 99-108, (2012) (PubMed).
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- Histone 3 (H3) (Histone H3 (H3))
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别名
- Histone H3
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背景
- Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
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分子量
- 17 kDa
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NCBI登录号
- NP_003520, NM_003529
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UniProt
- P68431
抗原
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