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Ezrin 抗体 (pTyr353)

EZR 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1355833
发货至: 中国
  • 抗原 See all Ezrin (EZR) 抗体
    Ezrin (EZR)
    抗原表位
    • 29
    • 16
    • 12
    • 11
    • 9
    • 9
    • 9
    • 8
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr353
    适用
    • 154
    • 81
    • 74
    • 8
    • 7
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 142
    • 11
    • 3
    • 2
    克隆类型
    • 138
    • 19
    多克隆
    标记
    • 90
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This Ezrin antibody is un-conjugated
    应用范围
    • 118
    • 54
    • 26
    • 17
    • 16
    • 13
    • 13
    • 13
    • 10
    • 9
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    特异性
    The antibody detects endogenous level of Ezrin only when phosphorylated at tyrosine 353.
    免疫原
    Peptide sequence around phosphorylation site of pTyr353 (Q-D-Y (p) -E-E) derived from Human EZRIN. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
    Top Product
    Discover our top product EZR Primary Antibody
  • 应用备注
    Western blotting: 1:500-1:1000
    Immunohistochemistry: 1:50-1:100  
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • Oda, Aishima, Morimatsu, Hayashi, Shindo, Fujino, Mizuuchi, Hattori, Tanaka, Oda: "Differential ezrin and phosphorylated ezrin expression profiles between pancreatic intraepithelial neoplasia, intraductal papillary mucinous neoplasm, and invasive ductal carcinoma of the pancreas." in: Human pathology, Vol. 44, Issue 8, pp. 1487-98, (2013) (PubMed).

    Morimatsu, Aishima, Kayashima, Hayashi, Nakata, Oda, Taguchi, Tsuneyoshi, Tanaka, Oda: "Liver-intestine cadherin expression is associated with intestinal differentiation and carcinogenesis in intraductal papillary mucinous neoplasm." in: Pathobiology : journal of immunopathology, molecular and cellular biology, Vol. 79, Issue 2, pp. 107-14, (2012) (PubMed).

    Cui, Li, Zhang, Han: "Expression of Ezrin and phosphorylated Ezrin (pEzrin) in pancreatic ductal adenocarcinoma." in: Cancer investigation, Vol. 28, Issue 3, pp. 242-7, (2010) (PubMed).

  • 抗原
    Ezrin (EZR)
    别名
    Ezrin (EZR 产品)
    别名
    CVIL antibody, CVL antibody, VIL2 antibody, ezr antibody, vil2 antibody, wu:fc05c03 antibody, wu:fj31d06 antibody, cvil antibody, cvl antibody, Vil2 antibody, AW146364 antibody, R75297 antibody, p81 antibody, ezr.S antibody, ezrin antibody, ezrin b antibody, ezrin L homeolog antibody, EZR antibody, ezrb antibody, ezr antibody, Ezr antibody, ezr.L antibody
    背景
    Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.
    分子量
    81 kDa
    NCBI登录号
    NP_001104
    UniProt
    P15311
    途径
    Maintenance of Protein Location
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