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Cytochrome C 抗体 (AA 71-75)

This 兔 多克隆 anti-Cytochrome C antibody specifically detects Cytochrome C in WB. The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN1355829
发货至: 中国
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Quick Overview for Cytochrome C 抗体 (AA 71-75) (ABIN1355829)

抗原

See all Cytochrome C (CYCS) 抗体
Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))

适用

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人, 大鼠, 小鼠

宿主

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克隆类型

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多克隆

标记

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This Cytochrome C antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 71-75

    特异性

    The antibody detects endogenous level of total Cytochrome C protein.

    免疫原

    Peptide sequence around AA 71-75 (N-P-K-K-Y) derived from Human Cytochrome C.
  • 应用备注

    Western blotting: 1: 500-1: 1000

    限制

    仅限研究用
  • 状态

    Liquid

    储存条件

    4 °C/-20 °C
  • 抗原

    Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))

    别名

    Cytochrome C

    背景

    Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.

    分子量

    14 kDa

    途径

    Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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