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Cytochrome C 抗体 (AA 71-75)

This anti-Cytochrome C antibody is a 兔 多克隆 antibody detecting Cytochrome C in WB. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN1355829
发货至: 中国

Quick Overview for Cytochrome C 抗体 (AA 71-75) (ABIN1355829)

抗原

See all Cytochrome C (CYCS) 抗体
Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))

适用

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  • 41
  • 18
  • 5
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  • 1
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人, 大鼠, 小鼠

宿主

  • 111
  • 97
  • 5
  • 1

克隆类型

  • 135
  • 78
  • 1
多克隆

标记

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  • 16
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  • 2
  • 2
  • 1
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  • 1
  • 1
This Cytochrome C antibody is un-conjugated

应用范围

  • 166
  • 90
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Western Blotting (WB)
  • 抗原表位

    • 41
    • 16
    • 9
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 71-75

    特异性

    The antibody detects endogenous level of total Cytochrome C protein.

    免疫原

    Peptide sequence around AA 71-75 (N-P-K-K-Y) derived from Human Cytochrome C.
  • 应用备注

    Western blotting: 1: 500-1: 1000

    限制

    仅限研究用
  • 状态

    Liquid

    储存条件

    4 °C/-20 °C
  • 抗原

    Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))

    别名

    Cytochrome C

    背景

    Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.

    分子量

    14 kDa

    途径

    Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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