Cytochrome C 抗体 (AA 71-75)
Quick Overview for Cytochrome C 抗体 (AA 71-75) (ABIN1355829)
抗原
See all Cytochrome C (CYCS) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 71-75
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特异性
- The antibody detects endogenous level of total Cytochrome C protein.
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免疫原
- Peptide sequence around AA 71-75 (N-P-K-K-Y) derived from Human Cytochrome C.
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应用备注
- Western blotting: 1: 500-1: 1000
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限制
- 仅限研究用
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状态
- Liquid
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储存条件
- 4 °C/-20 °C
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- Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))
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别名
- Cytochrome C
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背景
- Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.
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分子量
- 14 kDa
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途径
- Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
抗原
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