CD45RA/B 抗体 (PE)
CD45RA/B
适用: 大鼠
FACS
宿主: 小鼠
Monoclonal
OX-33
PE
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- 抗原 See all CD45RA/B products
- CD45RA/B
- 适用
- 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD45RA/B antibody is conjugated to PE
- 应用范围
- Flow Cytometry (FACS)
- 特异性
- Rat CD45RA/B
- 免疫原
- Rat purified spleen L-CA . Fusion Partner: NSO/U . Donor: BALB/c spleen
- 克隆位点
- OX-33
- 亚型
- IgG1
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- 限制
- 仅限研究用
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- 浓度
- 0.5 µg/10 cells
- 储存条件
- 4 °C
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- 抗原
- CD45RA/B
- 别名
- CD45RA/B (CD45RA/B 产品)
- 背景
- Rat Leukocyte Common Antigen has been shown to exist in different forms on different lymphoid cell types. Rat L-CA on thymocytes shows one main band at 180 kDa, T cells show 4 bands at 180, 190, 200 and 220 kDa. ABIN133316detects a subfraction of the 240 kDa rat L-CA band found only on B lymphocytes. This monoclonal antibody is of particular use in the investigation of the molecular and antigenic heterogeneity of rat L-CA, especially when used in conjunction with other OX antibodies. Four mouse monoclonal antibodies (MRC OX 1, 28, 29 and 30) react with all molecular forms of L-CA and fall into two sets that are non- competitive in binding to L-CA (MRC OX 1, 28, 29 and 30). The antigenic determinants seen by all these antibodies are lost when L-CA is reduced and alkylated. Three antibodies (MRC OX 22, 31, and 32) react selectively with B cells, T cytotoxic cells and about two thirds of T helper cells. OX 22 and OX 31 compete for binding but are non- competitive with OX 32. All of these antibodies bind to a sub-fraction of the 190, 200 and 220 kDa forms of T cell L-CA but not at all to the 180 kDa form of T cells or thymocytes.
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