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CD8 alpha 抗体

CD8A 适用: 大鼠 FACS 宿主: 小鼠 Monoclonal OX-8 unconjugated
产品编号 ABIN133184
发货至: 中国
  • 抗原 See all CD8 alpha (CD8A) 抗体
    CD8 alpha (CD8A) (CD8a Molecule (CD8A))
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    大鼠
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    小鼠
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    单克隆
    标记
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    This CD8 alpha antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS)
    特异性
    Rat CD8a
    纯化方法
    Ion exchange column
    免疫原
    High molecular weight rat thymocyte glycoproteins . Fusion Partner: P3-NSI-1-Ag4 (NS1/1) . Donor: BALB/c spleen
    克隆位点
    OX-8
    亚型
    IgG1
    Top Product
    Discover our top product CD8A Primary Antibody
  • 应用备注
    This clone is reported to work with frozen and paraffin sections (9).
    限制
    仅限研究用
  • 浓度
    0.1 µg/10 cells
    储存条件
    4 °C
  • 抗原
    CD8 alpha (CD8A) (CD8a Molecule (CD8A))
    别名
    CD8a (CD8A 产品)
    别名
    cd8 antibody, LOC100136450 antibody, BB154331 antibody, Ly-2 antibody, Ly-35 antibody, Ly-B antibody, Lyt-2 antibody, zgc:136643 antibody, CD8 antibody, Leu2 antibody, MAL antibody, p32 antibody, RHACD8-4 antibody, CD8a molecule antibody, uncharacterized LOC100125537 antibody, CD8 alpha antibody, CD8 antigen, alpha chain antibody, T-cell surface glycoprotein CD8 alpha chain antibody, Cd8a antibody, LOC100125537 antibody, LOC100136450 antibody, CD8A antibody, cd8a antibody, LOC100126556 antibody
    背景
    Anti-rat T cytotoxic/suppressor cell monoclonal antibody recognizes a determinant on the majority of thymocytes (90-95%), a subset of peripheral T cells, the majority of NK cells, and the granular intraepithelial leukocytes in the small intestine (1,2,3,4). The antigen recognized is a complex of surface glycoproteins of Mr 34, 39, and 76 kDa and is the rat homologue of the human CD8 and the mouse Ly 2.3 antigen (5,8). ABIN133184labels all peripheral T cells that are unlabelled by the ABIN133184(W3/25) monoclonal antibody. It labels a T cell subset which mediates the suppression of antibody formation (1) and the cytotoxic cell precursor (2). ABIN133184and ABIN133184can be used together to fractionate T cells by sorting in FACS or by rosette depletion (1,2) or can be used together to study subsets of T cells in the rat which mediate lethal graft versus host disease (7). This antibody is one of the 3 monoclonal antibodies which labels T lymphocyte populations in the rat, these being ABIN133184(W3/13) which labels all T cells, as well as ABIN133184(W3/25) and ABIN133184(MRC OX-8) which label non-overlapping T cell populations. These monoclonal antibodies used in concert are being employed extensively to investigate cellular aspects of the immune response in rats and prove to be useful as markers for functionally distinct subpopulations of lymphocytes. This clone is reported to work with frozen and paraffin sections (9).
    途径
    TCR Signaling
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