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FGFR4 抗体 (PE)

This anti-FGFR4 antibody is a 小鼠 单克隆 antibody detecting FGFR4 in FACS. Suitable for 人.
产品编号 ABIN1303110
发货至: 中国

Quick Overview for FGFR4 抗体 (PE) (ABIN1303110)

抗原

See all FGFR4 抗体
FGFR4 (Fibroblast Growth Factor Receptor 4 (FGFR4))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This FGFR4 antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS)

克隆位点

4FR6D3
  • 原理

    Anti-Hu CD334 PE

    特异性

    The mouse monoclonal antibody 4FR6D3 reacts with an extracellular epitope of CD334, the fibroblast growth factor receptor 4, which is an approximately 88 kDa receptor tyrosine kinase expressed in variety of tissues.

    交叉反应 (详细)

    Human

    纯化方法

    Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

    免疫原

    NIH 3T3 cells transfected with full length human CD334

    亚型

    IgG1 kappa
  • 应用备注

    Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

    限制

    仅限研究用
  • 缓冲液

    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • 抗原

    FGFR4 (Fibroblast Growth Factor Receptor 4 (FGFR4))

    别名

    CD334

    背景

    Fibroblast growth factor receptor 4,CD334 / FGFR4 (fibroblast growth factor receptor 4), a transmembrane tyrosine kinase, which is expressed in many tissues, such as in lung, kidney, muscle, heart, pancreas, intestine and other, acts as a receptor for several fibroblast growth factors, namely FGF1, FGF2, FGF6, FGF8, and FGF19. Interaction with these growth factors initiates in cell the signaling cascades leading to the mitogenesis and cell differentiation. Presence of CD334 Gly338Arg allele correlates with prognostic parameters in various cancer studies. CD334 plays multiple roles in the organism, including those of muscle regeneration, cholesterol-to-bile acid metabolism, or glucose homeostasis.,FGFR4, TKF, JTK2, FGFR-4

    基因ID

    2264

    UniProt

    P22455

    途径

    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding
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