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FGFR4 抗体 (full length)

The 小鼠 单克隆 anti-FGFR4 antibody (Clone 4FR6D3) (ABIN1302415) specifically detects FGFR4 in FACS 和 ICC. The antibody is reactive with 人 samples.
产品编号 ABIN1302415
发货至: 中国
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Room 801-803
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Quick Overview for FGFR4 抗体 (full length) (ABIN1302415)

抗原

See all FGFR4 抗体
FGFR4 (Fibroblast Growth Factor Receptor 4 (FGFR4))

适用

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宿主

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小鼠

克隆类型

  • 64
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单克隆

标记

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This FGFR4 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunocytochemistry (ICC)

克隆位点

4FR6D3
  • 抗原表位

    • 15
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    full length

    原理

    Anti-Hu CD334 Purified

    交叉反应 (详细)

    Human

    产品特性

    The mouse monoclonal antibody 4FR6D3 reacts with an extracellular epitope of CD334, the fibroblast growth factor receptor 4, which is an approximately 88 kDa receptor tyrosine kinase expressed in variety of tissues.

    纯化方法

    Purified by protein-A affinity chromatography.

    纯度

    > 95 % (by SDS-PAGE)

    免疫原

    NIH 3T3 cells transfected with full length human CD334

    亚型

    IgG1, kappa
  • 应用备注

    Flow cytometry: Recommended dilution: 2-6 μg/mL.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Do not freeze

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Do not freeze.
  • 抗原

    FGFR4 (Fibroblast Growth Factor Receptor 4 (FGFR4))

    别名

    CD334

    背景

    Fibroblast growth factor receptor 4,CD334 / FGFR4 (fibroblast growth factor receptor 4), a transmembrane tyrosine kinase, which is expressed in many tissues, such as in lung, kidney, muscle, heart, pancreas, intestine and other, acts as a receptor for several fibroblast growth factors, namely FGF1, FGF2, FGF6, FGF8, and FGF19. Interaction with these growth factors initiates in cell the signaling cascades leading to the mitogenesis and cell differentiation. Presence of CD334 Gly338Arg allele correlates with prognostic parameters in various cancer studies. CD334 plays multiple roles in the organism, including those of muscle regeneration, cholesterol-to-bile acid metabolism, or glucose homeostasis.,FGFR4, TKF, JTK2, FGFR-4

    基因ID

    2264

    UniProt

    P22455

    途径

    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding
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