电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

ASAP1 抗体 (AA 777-787)

ASAP1 适用: 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN129670
发货至: 中国
  • 抗原 See all ASAP1 抗体
    ASAP1 (ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 1 (ASAP1))
    抗原表位
    • 15
    • 8
    • 7
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 777-787
    适用
    • 43
    • 35
    • 10
    • 6
    • 1
    • 1
    • 1
    小鼠
    宿主
    • 52
    • 2
    • 1
    克隆类型
    • 53
    • 2
    多克隆
    标记
    • 20
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This ASAP1 antibody is un-conjugated
    应用范围
    • 43
    • 26
    • 13
    • 13
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA
    交叉反应
    小鸡, 绵羊, 犬, 大鼠, Chimpanzee
    产品特性
    Concentration Definition: by UV absorbance at 280 nm
    免疫原
    This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 777-787 of mouse ASAP1 protein (see below).
    亚型
    IgG
    Top Product
    Discover our top product ASAP1 Primary Antibody
  • 应用备注
    This affinity purified antibody has been tested for use in ELISA, IF microscopy and by western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 130 kDa in size corresponding to ASAP1 protein by western blotting in the appropriate cell lysate or extract.  This antibody recognizes both phosphorylated and non-phosphorylated ASAP1 at amino acid Y782.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.95 mg/mL
    缓冲液
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • Sato, Zhao, Imai, Simister, Feller, Trackman, Kirsch, Sonenshein: "Inhibition of CIN85-mediated invasion by a novel SH3 domain binding motif in the lysyl oxidase propeptide." in: PLoS ONE, Vol. 8, Issue 10, pp. e77288, (2013) (PubMed).

  • 抗原
    ASAP1 (ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 1 (ASAP1))
    别名
    ASAP1 (ASAP1 产品)
    别名
    AV239055 antibody, DEF-1 antibody, Ddef1 antibody, PAP antibody, mKIAA1249 antibody, s19 antibody, AMAP1 antibody, CENTB4 antibody, DDEF1 antibody, PAG2 antibody, ZG14P antibody, ASAP1 antibody, ddef1 antibody, Asap1 antibody, si:ch211-160i2.3 antibody, ArfGAP with SH3 domain, ankyrin repeat and PH domain1 antibody, ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 antibody, toxic extracellular endopeptidase antibody, ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 L homeolog antibody, ArfGAP with SH3 domain, ankyrin repeat and PH domain 1a antibody, Asap1 antibody, ASAP1 antibody, asaP1 antibody, asap1 antibody, asap1.L antibody, asap1a antibody
    背景
    This antibody is designed, produced, and is suitable for Cancer, Immunology and Nuclear Signaling research. ASAP1 (also known as AMAP1, 130-kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase-activating protein, PIP2-dependent ARF1 GAP, ADP-ribosylation factor-directed GTPase-activating protein 1, ARF GTPase-activating protein 1, Development and differentiation-enhancing factor 1, Differentiation-enhancing factor 1, DEF-1) is an Arf-directed GTPase activating protein that is a substrate for the kinases Src and FAK and has been implicated in the regulation of membrane traffic, focal adhesions and invadopodia/podosomes.  Phosphorylation of ASAP1 at tyrosine 782 has been found to affect enzymatic and some biological activities, including the function of invadopodia. ASAP1 is expressed in many tissues but is most abundant in the testis, brain, lung and spleen. A heightened expression was seen in the adipose tissue from obese (ob) and diabetic (db) animals. Multiple transcript variants have been reported for this protein.
    Synonyms: Development and differentiation enhancing factor 1 antibody, 130 kDa phosphatidylinositol 4 5 biphosphate dependent ARF1 GTPase activating protein antibody, ADP ribosylation factor directed GTPase activating protein 1 antibody, AMAP 1 antibody
    基因ID
    13196, 65301464
    UniProt
    Q9QWY8
You are here:
客服