NCAPH 抗体 (AA 440-457)
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- 抗原 See all NCAPH 抗体
- NCAPH (Non-SMC Condensin I Complex, Subunit H (NCAPH))
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抗原表位
- AA 440-457
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NCAPH antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 产品特性
- Concentration Definition: by UV absorbance at 280 nm
- 免疫原
- This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 440-457 of Human BRRN-1.
- 亚型
- IgG
- Top Product
- Discover our top product NCAPH Primary Antibody
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anti-Non-SMC Condensin I Complex, Subunit H (NCAPH) (AA 645-741) antibody
NCAPH 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C9 unconjugated
anti-Non-SMC Condensin I Complex, Subunit H (NCAPH) antibodyNCAPH 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Non-SMC Condensin I Complex, Subunit H (NCAPH) (AA 1-250) antibodyNCAPH 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Non-SMC Condensin I Complex, Subunit H (NCAPH) (AA 354-382) antibodyNCAPH 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB39349 unconjugated
anti-Non-SMC Condensin I Complex, Subunit H (NCAPH) (N-Term) antibodyNCAPH 适用: 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Non-SMC Condensin I Complex, Subunit H (NCAPH) (AA 601-700) antibodyNCAPH 适用: 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Non-SMC Condensin I Complex, Subunit H (NCAPH) (AA 1-250) antibodyNCAPH 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Non-SMC Condensin I Complex, Subunit H (NCAPH) (AA 1-741) antibodyNCAPH 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Non-SMC Condensin I Complex, Subunit H (NCAPH) (C-Term) antibodyVerified NCAPH 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Non-SMC Condensin I Complex, Subunit H (NCAPH) (C-Term) antibodyNCAPH 适用: 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 猴, 马, 兔, Pig, Bat WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- This affinity purified antibody has been tested for use in ELISA and by western blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 83 kDa in size corresponding to human BRRN1 by western blotting in the appropriate cell lysate or extract.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.93 mg/mL
- 缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
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- 抗原
- NCAPH (Non-SMC Condensin I Complex, Subunit H (NCAPH))
- 别名
- BRRN-1 (NCAPH 产品)
- 别名
- NCAPH antibody, si:dkeyp-86b9.4 antibody, zgc:158618 antibody, BRRN1 antibody, CAP-H antibody, brrn1 antibody, cap-h antibody, A730011O11Rik antibody, Brrn1 antibody, HCAP-H antibody, mKIAA0074 antibody, non-SMC condensin I complex subunit H antibody, non-SMC condensin I complex, subunit H antibody, condensin complex subunit 2 antibody, non-SMC condensin I complex subunit H S homeolog antibody, NCAPH antibody, ncaph antibody, LOC708975 antibody, ncaph.S antibody, Ncaph antibody
- 背景
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BRNN1, also called Barren, Condensin subunit 2, Barren homolog protein 1, Chromosome-associated protein H, hCAP-H, and XCAP-H homolog, is encoded by a gene that is a member of the barr gene family. Brnn1 is the regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. The condensin complex contains the SMC2L1 and SMC4L1 heterodimer, and three non SMC subunits that probably regulate the complex: BRRN1/CAPH, CNAP1/CAPD2 and CAPG. BRRN1 has both a nuclear and cytoplasmic localization. In interphase cells, the majority of the condensin complex is found in the cytoplasm, while a minority of the complex is associated with chromatin. A subpopulation of the complex however remains associated with chromosome foci in interphase cells. During mitosis, most of the condensin complex is associated with the chromatin. At the onset of prophase, the regulatory subunits of the complex are phosphorylated by CDC2 leading to condensin's association with chromosome arms and to chromosome condensation. Dissociation from chromosomes is observed in late telophase. BRRN1 is widely expressed at low level in most proliferating cells. CDC2 phosphorylates BRRN1. Its phosphorylation, as well as that of CNAP1 and CAPG subunits, activates the condensin complex and is required for chromosome condensation.
Synonyms: Barren Drosophila Homolog of 1 antibody, Barren homolog protein 1 antibody, BRRN antibody, CAP H antibody, CAPH antibody, Chromosome associated protein H antibody, Condensin complex subunit 2 antibody, Condensin subunit 2 antibody - 基因ID
- 23397
- UniProt
- Q15003
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