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JNK 抗体 (C-Term)
MAPK8
适用: 人, 小鼠, 大鼠
WB, IHC (p), IP
宿主: 兔
Polyclonal
unconjugated
JNK抗体详情
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抗原
See all JNK (MAPK8) 抗体
JNK (MAPK8)
(Mitogen-Activated Protein Kinase 8 (MAPK8))
抗原表位
All epitopes for JNK 抗体
C-Term
适用
All reactivities for JNK 抗体
人, 小鼠, 大鼠
宿主
All hosts for JNK 抗体
兔
克隆类型
All clonalities for JNK 抗体
多克隆
标记
All conjugates for JNK 抗体
This JNK antibody is un-conjugated
应用范围
All applications for JNK 抗体
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
特异性
The antibody detects the 46 kDa JNK1.
纯化方法
Immunoaffinity Chromatography.
免疫原
Synthetic peptide mapping to the C-terminus of human JNK-1
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Discover our top product MAPK8 Primary Antibody
Alternatives
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anti-Mitogen-Activated Protein Kinase 8 (MAPK8) (pThr183), (pTyr185) antibody
MAPK8
适用: 人, 小鼠, 大鼠, 犬, 兔
WB, ELISA, IHC (p), FACS, IF (cc), IF (p), ICC, IHC (fro)
宿主: 兔
Polyclonal
unconjugated
anti-Mitogen-Activated Protein Kinase 8 (MAPK8) (AA 201-300) antibody
MAPK8
适用: 人, 小鼠, 大鼠, 小鸡, 犬
WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro)
宿主: 兔
Polyclonal
unconjugated
anti-Mitogen-Activated Protein Kinase 8 (MAPK8) (AA 151-250) antibody
MAPK8
适用: 人, 小鼠, 大鼠, 小鸡, Pig
WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro)
宿主: 兔
Polyclonal
unconjugated
使用细节
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应用备注
Western Blot: 1 μg/mL. Immunoprecipitation: 10-20 μg/mL. Immunohistochemistry: 10-20 μg/mL. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
限制
仅限研究用
贮存及处理
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浓度
0.5 mg/mL
缓冲液
PBS pH 7.2, containing 50 % Glycerol, 1 % BSA, 0.02 % Thimerosal.
储存液
Thimerosal (Merthiolate)
注意事项
This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Avoid repeated freezing and thawing.
储存条件
-20 °C/-80 °C
储存方法
Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
JNK目标详情
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抗原
JNK (MAPK8)
(Mitogen-Activated Protein Kinase 8 (MAPK8))
别名
MAPK8 / JNK1 (MAPK8 产品 )
别名
JNK antibody, JNK-46 antibody, JNK1 antibody, JNK1A2 antibody, JNK21B1/2 antibody, PRKM8 antibody, SAPK1 antibody, SAPK1c antibody, AI849689 antibody, Prkm8 antibody, BSK antibody, BSK/DJNK antibody, Bsk antibody, CG5680 antibody, D-JNK antibody, D-junk antibody, DBSK/JNK antibody, DJNK antibody, DJNK/bsk antibody, Dmel\\CG5680 antibody, JNK/SAPK antibody, Jnk antibody, Junk antibody, SAPKa antibody, c-Jun antibody, dJNK antibody, jnk antibody, T10F20.15 antibody, jnk1 antibody, sapk1 antibody, mapk8 antibody, zgc:112379 antibody, JNKb antibody, mapk8b antibody, mitogen-activated protein kinase 8 antibody, Stress-activated protein kinase jnk-1 antibody, basket antibody, Protein kinase superfamily protein antibody, mitogen-activated protein kinase 8 L homeolog antibody, mitogen-activated protein kinase 8b antibody, mitogen-activated protein kinase 8B-like antibody, MAPK8 antibody, jnk-1 antibody, Mapk8 antibody, bsk antibody, ATMPK8 antibody, mapk8.L antibody, mapk8b antibody, LOC109094263 antibody
背景
The JNK pathway is activated by largely distinct stimuli including inflammatory cytokines (such as TNF-alpha and IL-1), UV light, inhibitors of protein synthesis and osmotic stress. Activated MEKK1 phosphorylates SEK1 (also known as MKK4), which in turn activates SAPK (also known as JNK). JNK binds tightly to the N-terminal region of c-Jun and ATF-2, and phosphorylates c-Jun at Ser63 and Ser73 and ATF-2 at Thr69 and Thr71.Synonyms: JNK-1, JNK-46, Mitogen-activated protein kinase 8, PRKM8, Stress-activated protein kinase JNK1, c-Jun N-terminal kinase 1
基因ID
5599
NCBI登录号
NP_002741
UniProt
P45983
途径
MAPK Pathway , WNT signaling , TLR signaling , Fc-epsilon Receptor Signaling Pathway , Neurotrophin Signaling Pathway , Activation of Innate immune Response , Hepatitis C , Toll-Like Receptors Cascades , Signaling of Hepatocyte Growth Factor Receptor , S100 Proteins
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