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Phospholipase C gamma 2 抗体 (C-Term)

The 兔 多克隆 anti-Phospholipase C gamma 2 antibody is suitable to detect Phospholipase C gamma 2 in samples from 人, 大鼠 和 小鼠. It has been validated for WB, IHC (p) 和 IP.
产品编号 ABIN127211
发货至: 中国
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Quick Overview for Phospholipase C gamma 2 抗体 (C-Term) (ABIN127211)

抗原

See all Phospholipase C gamma 2 (PLCG2) 抗体
Phospholipase C gamma 2 (PLCG2)

适用

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  • 1
人, 大鼠, 小鼠

宿主

  • 120
  • 6

克隆类型

  • 112
  • 14
多克隆

标记

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This Phospholipase C gamma 2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
  • 抗原表位

    • 29
    • 16
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    • 5
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    C-Term

    特异性

    The antibody recognizes 150 kDa PLCγ2. The antibody does not cross-react with PLCγ1.

    纯化方法

    Affinity purified

    免疫原

    Synthetic peptide near the C-terminus of human PLCgamma2.
  • 应用备注

    Western Blot: 1-4 μg/mL. Immunoprecipitation: 20 μg/mL. Immunohistochemistry: 20 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    PBS, pH 7.2, containing 50 % glycerol, 1 % BSA, 0.02 % thimerosal.

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C/-80 °C

    储存方法

    Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
  • 抗原

    Phospholipase C gamma 2 (PLCG2)

    别名

    PLCG2

    背景

    PLC (Phosphoinositide-specific phospholipase C) plays a significant role in transmembrane signaling. Four members of PLCs have been identified: PLCβ, PLCγ, PLCδ, and PLCε. In response to extracellular stimuli (e.g., hormone, growth factors, neurotransmitters), PLC hydrolizes phosphatidylinositol 4,5-biphosphate (PIP2) into two secondary messengers: inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG). PLCγ2 is engaged in antigen-dependent signaling in B-cells and collagen-dependent signaling in platelets.Synonyms: 1-phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma-2, PLC-IV, PLC-gamma-2, Phosphoinositide phospholipase C-gamma-2, Phospholipase C-IV, Phospholipase C-gamma-2

    基因ID

    5336

    NCBI登录号

    NP_002652

    UniProt

    P16885

    途径

    RTK signaling, WNT signaling, Fc-epsilon Receptor Signaling Pathway, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades, VEGF Signaling, BCR Signaling
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