RIPK1 抗体
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北京 101111
Quick Overview for RIPK1 抗体 (ABIN127073)
抗原
See all RIPK1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- The antibody detects 74 kDa RIP in Western blot analysis.
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交叉反应 （详细）
- Species reactivity (tested):Human, Mouse and Rat.
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纯化方法
- Affinity Chromatography.
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免疫原
- Synthetic peptide surrounding amino acid 645 of Human RIP
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anti-Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1) (AA 1-179) antibody
RIPK1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1) (AA 17-289) antibodyRIPK1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1) (AA 133-422) antibodyRIPK1 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2D6 unconjugated
anti-Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1) (AA 131-277) antibodyRIPK1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3B5B6 unconjugated
anti-Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1) antibodyKD Validated RIPK1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB2140 unconjugated Recombinant Antibody
anti-Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1) (AA 411-425), (Middle Region) antibodyRIPK1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1) (AA 328-458) antibodyRIPK1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1) (AA 1-656) antibodyRIPK1 适用: 小鼠 ELISA, IP 宿主: 兔 Polyclonal unconjugated
anti-Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1) antibodyRIPK1 适用: 人 WB, IP 宿主: 兔 Monoclonal unconjugated
anti-Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1) (AA 133-422) antibodyRIPK1 适用: 人, 犬 WB 宿主: 小鼠 Monoclonal 2A8 unconjugated
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应用备注
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Western Blot: 2-6 μg/mL. Immunoprecipitation. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS, pH 7.2, containing 30 % Glycerol, 0.5 % BSA as stabilizer and 0.01 % Thimerosal as preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C/-80 °C
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储存方法
- Store the antibody undiluted at -20 °C or (in aliquots) at -70 °C for long term storage.
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- RIPK1 (Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1))
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别名
- RIP
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背景
- RIP (Receptor Interacting Protein) is a 74 kDa Ser/Thr kinase which interacts with CD95 (Fas/Apo1) receptor and the tumor necrosis factor receptor (TNFR1). It is a cell death domain adapter protein which can bind to the adapter proteins TRADD, RAID, and TRAF2. RIP contains an N-terminal region with homology to protein kinase, an intermediate domain capable of association with MAPKKK and a C-terminal region containing an intracellular death domain motif. RIP activates both p38 MAP kinase and SAPK families. In vitro, RIP induces apoptosis, as well as SAPK/JNK and NF-kB activation. RIP possesses kinase activity as it autophosphorylates itself on serine and threonine residues.Synonyms: Cell death protein RIP, RIPK1, Receptor-Interacting Protein, Receptor-interacting serine/threonine-protein kinase 1, Serine/threonine-protein kinase RIP
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基因ID
- 8737
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NCBI登录号
- NP_003795
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UniProt
- Q13546
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途径
- NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, TLR signaling, Activation of Innate immune Response, Inositol Metabolic Process, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interactome, Ubiquitin Proteasome Pathway
抗原
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