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SPTAN1 抗体

SPTAN1 适用: 人, 小鼠, 大鼠, 小鸡 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN127066
发货至: 中国
  • 抗原 See all SPTAN1 抗体
    SPTAN1 (Spectrin alpha Chain, Brain (SPTAN1))
    适用
    • 76
    • 39
    • 39
    • 20
    • 6
    • 5
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    • 4
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    • 3
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    • 1
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    人, 小鼠, 大鼠, 小鸡
    宿主
    • 100
    • 15
    • 1
    克隆类型
    • 92
    • 24
    多克隆
    标记
    • 58
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    • 3
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    • 1
    • 1
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    This SPTAN1 antibody is un-conjugated
    应用范围
    • 80
    • 45
    • 21
    • 20
    • 15
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    • 14
    • 11
    • 9
    • 7
    • 5
    • 3
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    Affinity Chromatography
    免疫原
    Synthetic peptide surrounding amino acid 162 of Mouse alpha-Fodrin.
    亚型
    IgG
    Top Product
    Discover our top product SPTAN1 Primary Antibody
  • 应用备注
    Western Blot: 0.5-4 μg/mL. Immunohistochemistry: 10-20 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    PBS, pH 7.2 containing 30 % Glycerol, 0.5 % BSA and 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C/-80 °C
    储存方法
    Store the antibody undiluted at -20 °C or (in aliquots) at -70 °C for long term storage .
  • 抗原
    SPTAN1 (Spectrin alpha Chain, Brain (SPTAN1))
    别名
    Spectrin alpha Chain (Brain) / SPTAN1 (SPTAN1 产品)
    别名
    im:7157190 antibody, wu:fa20e05 antibody, wu:fb33g08 antibody, wu:fk32a10 antibody, zgc:112229 antibody, 2610027H02Rik antibody, Spna-2 antibody, Spna2 antibody, EIEE5 antibody, NEAS antibody, SPTA2 antibody, A2a antibody, IPF antibody, SPECA antibody, spectrin alpha, non-erythrocytic 1 antibody, spectrin, alpha, non-erythrocytic 1 antibody, SPTAN1 antibody, sptan1 antibody, Sptan1 antibody
    背景
    Fodrin is a universally expressed membrane-associated cytoskeletal protein consisting of α- and β-subunits. The protein is important for maintaining normal membrane structure and supporting cell surface protein function. α-Fodrin is one of the important targets cleaved by caspases during apoptosis. The full length 240 kDa protein can be cleaved at several sites within its sequence by activated caspases generating N-terminal 150 kDa, C-terminal 120 kDa, and 35 kDa major products. Cleavage of α-Fodrin leads to membrane malfunction and cell shrinkage.Synonyms: Alpha-II spectrin, Fodrin alpha chain, SPTA2, Spectrin non-erythroid alpha chain
    基因ID
    10090
    UniProt
    P16546
    途径
    Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization
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