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Bcl-2 抗体 (N-Term)

BCL2 适用: 人, 小鼠, 大鼠 WB, IP, IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN126981
发货至: 中国
  • 抗原 See all Bcl-2 (BCL2) 抗体
    Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
    抗原表位
    • 48
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    N-Term
    适用
    • 428
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    人, 小鼠, 大鼠
    宿主
    • 346
    • 104
    • 6
    • 2
    • 1
    克隆类型
    • 345
    • 113
    多克隆
    标记
    • 202
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    This Bcl-2 antibody is un-conjugated
    应用范围
    • 373
    • 187
    • 164
    • 112
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    • 64
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    • 28
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    Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    Detects a 25 kDa protein, corresponding to the apparent molecular weight of the alpha isoform of Bcl-2 on SDS-PAGE immunoblots.
    纯化方法
    Affinity-purified
    免疫原
    Synthetic peptide corresponding to the N-terminus of human Bcl-2
    Top Product
    Discover our top product BCL2 Primary Antibody
  • 应用备注
    Western blot analysis (0.5-4 μg/mL). Immunoprecipation (4-8 μg/mL). Immunohistochemistry on frozen sections (10-20 μg/mL).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.2 mg/mL
    缓冲液
    PBS, pH 7.2, containing 30 % glycerol, 0.5 % BSA, 0.01 % thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid Repeated freeze/defrost cycles.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. For long-term storage, aliquot and freeze at -20 °C to -70 °C.
  • 抗原
    Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
    别名
    Bcl-2 (BCL2 产品)
    别名
    Bcl-2 antibody, PPP1R50 antibody, bcl-2 antibody, AW986256 antibody, C430015F12Rik antibody, D630044D05Rik antibody, D830018M01Rik antibody, BCL-2 antibody, Bcl2 antibody, BCL2, apoptosis regulator antibody, B cell leukemia/lymphoma 2 antibody, B-cell CLL/lymphoma 2a antibody, B-cell CLL/lymphoma 2 protein antibody, BCL2 antibody, Bcl2 antibody, bcl2a antibody, BCL-2 antibody
    背景
    Bcl-2 and its homologs belong to a family of proteins that either promotes or prevent apoptosis. Bcl-2 alpha and beta are the alternatively spliced isoforms of 25 kDa and 22 kDa mitochondrial integral membrane proteins that inhibit apoptosis. Bcl-2 was identified as a gene translocated from chromosome 18 to the immunoglobulin (Ig) heavy chain locus on chromosome 14 in B lymphocytes, a condition that is associated with the onset of human follicular B cell lymphomas. This interchromosomal translocation leads to constitutive expression of Bcl-2, which results in increased survival and expansion of follicular center cell population.Synonyms: Apoptosis regulator Bcl-2, B-Cell CLL/lymphoma 2, BCL2, Bcl-2 alpha
    基因ID
    596
    NCBI登录号
    NP_000624
    UniProt
    P10415
    途径
    MAPK Pathway, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
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