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BAX 抗体 (N-Term)

This anti-BAX antibody is a 兔 多克隆 antibody detecting BAX in WB 和 IP. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN126979
发货至: 中国

Quick Overview for BAX 抗体 (N-Term) (ABIN126979)

抗原

See all BAX 抗体
BAX (BCL2-Associated X Protein (BAX))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This BAX antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP)
  • 抗原表位

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    N-Term

    特异性

    The antibody detects a 20 kDa protein, corresponding to the apparent molecular weight of Bax on SDS-PAGE Immunoblots.

    纯化方法

    Affinity Chromatography

    免疫原

    Synthetic peptide corresponding to amino acids near the N-terminus of Human Bax
  • 应用备注

    Western BLot: 0.5-4 μg/mL. Immunoprecipitation: 10-20 μg/mL. Rat kidney tissue lysate can be used as a positive control.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    PBS, pH 7.2, containing 30 % Glycerol, 0.5 % BSA and 0.01 % Thimerosal.

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C/-80 °C

    储存方法

    Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
  • 抗原

    BAX (BCL2-Associated X Protein (BAX))

    别名

    Bax

    背景

    The Bcl-2 (B-cell leukemia/lymphoma 2) family proteins function to either inhibit (Bcl-2 and Bcl-XL) or promote (Bax and Bak) apoptosis. Bax contains the conserved Bcl-2 homology 1 (BH1) and 2 (BH2) domains that allow for its homodimerization or heterodimerization with Bcl-2. When Bcl-2 is in excess, apoptosis is inhibited. However, if Bax levels increase in response to a death signal, the cell is pushed toward death.Synonyms: Apoptosis regulator BAX, BCL2-associated X protein, BCL2L4, Bcl-2-like protein 4, Bcl2-L-4

    基因ID

    9606

    UniProt

    Q07812

    途径

    p53 Pathway, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
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