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SERPINB9 抗体

SERPINB9 适用: 人 WB, IHC (p) 宿主: 小鼠 Monoclonal PI9-17 unconjugated
产品编号 ABIN126942
发货至: 中国
  • 抗原 See all SERPINB9 抗体
    SERPINB9 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 9 (SERPINB9))
    适用
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    宿主
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    小鼠
    克隆类型
    • 34
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    单克隆
    标记
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    This SERPINB9 antibody is un-conjugated
    应用范围
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    The antibody clone PI9-17 recognizes 42 kDa native PI-9 and the 63 kDa PI-9 complexed to Granzyme B.
    交叉反应 (详细)
    Species reactivity (tested):Human.
    产品特性
    Synonyms: PI9, Serpin B9, Cytoplasmic antiproteinase 3, CAP-3, CAP3, Proteinase inhibitor 9
    纯化方法
    Affinity Chromatography
    免疫原
    Recombinant human full length PI9
    克隆位点
    PI9-17
    亚型
    IgG1
    Top Product
    Discover our top product SERPINB9 Primary Antibody
  • 应用备注
    Western Blot: 2-4 μg/mL. Immunohistochemistry: 20 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    PBS, 0.02 % Thimerosal, 50 % Glycerol, 1 % BSA
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C/-80 °C
    储存方法
    Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    有效期
    12 months
  • 抗原
    SERPINB9 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 9 (SERPINB9))
    别名
    SERPINB9 (SERPINB9 产品)
    别名
    SERPINB9 antibody, BB283241 antibody, CAP-3 antibody, CAP3 antibody, PI-9 antibody, PI9 antibody, Spi6 antibody, ovalbumin antibody, serpin family B member 9 antibody, serpin peptidase inhibitor, clade B (ovalbumin), member 9 antibody, serine (or cysteine) peptidase inhibitor, clade B, member 9 antibody, Serpinb9 antibody, SERPINB9 antibody
    背景
    Proteinase inhibitor 9 (PI-9, also designated cytoplasmic antiproteinase 3, or CAP3) is a 42 kDa member of the ovalbumin family of serpins that is expressed in placenta, lung and cytotoxic lymphocytes. PI-9 is a potent inhibitor of granzyme B and of granzyme B-mediated apoptosis, and is also an inhibitor of capase-1 and, to a smaller extent, caspase-4 and caspase-8. PI-9 expression is also upregulated in response to inflammatory stimuli. This upregulation protects cells from apoptosis induced by endogenously expressed or released granzyme B, particulary during target cell killling.Synonyms: CAP-3, CAP3, Cytoplasmic antiproteinase 3, PI-9, PI9, Proteinase inhibitor 9, Serpin B9
    基因ID
    5272
    UniProt
    P50453
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