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MAP2K7 抗体

This 小鼠 单克隆 anti-MAP2K7 antibody (Clone 10F7) specifically detects MAP2K7 in WB, IF, IHC (fro) 和 EIA. The antibody is reactive with 人, 小鼠, 大鼠 和 犬 samples.
产品编号 ABIN126842
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for MAP2K7 抗体 (ABIN126842)

抗原

See all MAP2K7 抗体
MAP2K7 (Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7))

适用

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人, 小鼠, 大鼠, 犬

宿主

  • 112
  • 4
小鼠

克隆类型

  • 94
  • 22
单克隆

标记

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  • 5
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  • 5
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  • 1
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This MAP2K7 antibody is un-conjugated

应用范围

  • 85
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  • 9
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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

克隆位点

10F7
  • 特异性

    This antibody specifically recognizes the N-terminus of MKK7.

    产品特性

    Synonyms: MAPK/ERK kinase 7, JNK-activating kinase 2, c-Jun N-terminal kinase kinase 2, MAPKK 7,NKK2, MEK7, MKK7, MAP kinase kinase 7, Dual specificity mitogen-activated protein kinasekinase 7

    纯化方法

    Size exclusion chromatography

    组件

    incl. positive Control

    免疫原

    Synthetic peptide conjugated to KLH

    亚型

    IgG1
  • 应用备注

    Western Blot: 0.5 μg/mL for HRPO/ECL detection. Recommended blocking buffer: Casein/Tween 20 based blocking and blot incubationbuffer. Positive Control: Cell lysate from untreated SW480 cells. ELISA: 0.1 μg/mL. Immunocytochemistry. Immunohistochemistry on frozen sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 溶解方式

    Restore with 1 mL H2O (15 min, RT).

    缓冲液

    1 mL2 x PBS containing 0.09 % Sodium Azide, PEG and Sucrose

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C/-80 °C

    储存方法

    Store lyophilized (preferably in a desiccator) at -20 °C and reconstituted (aliquote andfreeze in liquid nitrogen) at -80 °C. Avoid repeated freezing and thawing. Thaw aliquots at 37 °C. Thawed aliquots may be stored at 4 °C up to 3 months.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    MAP2K7 (Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7))

    别名

    MAP2K7

    背景

    The stress response of mammalian cells results in activation of kinases of the SAPK1 and SAPK2 families. The SAP kinases are specifically activated by dual phosphorylation of a conserved T-X-Y motif by MAP kinase kinases (MKK). The 3 isoforms of the SAPK1 family (SAPK1α/jnk2, SAPK1β/jnk3, SAPK1γ/jnk1) are synergistically activated by phosphorylation of the threonine residue by MKK7 and the tyrosine residue by MKK4.Synonyms: Dual specificity mitogen-activated protein kinase kinase 7, JNK-activating kinase 2, MAP kinase kinase 7, MAPK/ERK kinase 7, MAPKK 7, MEK7, MKK7, NKK2, c-Jun N-terminal kinase kinase 2

    分子量

    45 kDa

    基因ID

    5609

    UniProt

    O14733

    途径

    MAPK Pathway, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, BCR Signaling
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