LEF1 抗体
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北京 101111
Quick Overview for LEF1 抗体 (ABIN126828)
抗原
See all LEF1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody specifically recognizes LEF at 55-57 kDa. It does not crossreact with TCF3 and TCF4.
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产品特性
- Synonyms: Lymphoid enhancer-binding factor 1, LEF-1, T cell-specific transcription factor 1-alpha,TCF1-alpha
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纯化方法
- Size exclusion chromatography
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免疫原
- Recombinant LEF
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亚型
- IgG1
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应用备注
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Western Blot: 0.5 μg/mL for HRPO/ECL detection. Recommended blocking buffer: Casein/Tween 20 based blocking and blot incubationbuffer. ELISA: 0.1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.1mg/mL
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缓冲液
- PBS/0.09 % Na-Azide/PEG and Sucrose/50 % Glycerol
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
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Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- LEF1 (Lymphoid Enhancer-Binding Factor 1 (LEF1))
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别名
- LEF1
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背景
- LEF is a transcription factor of the LEF/TCF protein family. LEF interacts with cytoplasmic beta-catenin and regulates the expression of genes containing a LEF/TCF binding site. The formation of LEF - beta-catenin heterodimers is an important step in the wnt/wg signal transduction pathway.Synonyms: LEF-1, Lymphoid enhancer-binding factor 1, T cell-specific transcription factor 1-alpha, TCF1-alpha
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基因ID
- 51176
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UniProt
- Q9UJU2
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途径
- WNT signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Hormone Metabolic Process, Nuclear Hormone Receptor Binding, Chromatin Binding
抗原
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