电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

IGF1R 抗体 (C-Term)

This anti-IGF1R antibody is a 小鼠 单克隆 antibody detecting IGF1R in WB. Suitable for 人.
产品编号 ABIN126815
发货至: 中国

Quick Overview for IGF1R 抗体 (C-Term) (ABIN126815)

抗原

See all IGF1R 抗体
IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))

适用

  • 194
  • 110
  • 94
  • 16
  • 8
  • 8
  • 7
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1

宿主

  • 181
  • 33
  • 2
  • 2
  • 1
小鼠

克隆类型

  • 180
  • 37
  • 1
单克隆

标记

  • 138
  • 8
  • 8
  • 8
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
This IGF1R antibody is un-conjugated

应用范围

  • 141
  • 76
  • 70
  • 63
  • 32
  • 28
  • 28
  • 19
  • 13
  • 13
  • 5
  • 4
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)

克隆位点

7G11
  • 抗原表位

    • 23
    • 23
    • 19
    • 14
    • 12
    • 12
    • 11
    • 10
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    特异性

    This antibody specifically recognizes the C-terminus of IGF1 receptor.

    产品特性

    Synonyms: IGF-I receptor, IGF1 Receptor, Insulin-like growth factor 1 receptor

    纯化方法

    Subsequent Thiophilic Adsorption and Size Exclusion Chromatography

    组件

    incl. positive Control

    免疫原

    Synthetic peptide conjugated to KLH.

    亚型

    IgG1
  • 应用备注

    Western Blot: 0.5 μg/mL for HRPO/ECL detection. Recommended blocking buffer: Casein/Tween 20 based blocking and blot incubationbuffer. Positive control: Cell lysate from untreated A431 cells.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 溶解方式

    Restore with 1 mL H2O (15 min, RT).

    缓冲液

    1 mL2 x PBS, 0.09 % Sodium Azide, PEG and Sucrose

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C/-80 °C

    储存方法

    Store lyophilized (preferably in a desiccator) at -20 °C and reconstituted (aliquote andfreeze in liquid nitrogen) at -80 °C. Avoid repeated freezing and thawing. Thaw aliquots at 37 °C. Thawed aliquots may be stored at 4 °C up to 3 months.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))

    别名

    CD221 / IGF1R

    背景

    The IGF1 receptor (IGF1R) is a heterodimeric receptor tyrosine kinase with an extracellular alpha-chain, a transmembrane domain and an intracellular beta-chain. The IGF1 receptor is activated upon binding of the peptide hormones IGF1 and 2, leading to autophosphorylation of tyrosine residue 1131, 1135, and 1136 in the activation loop of the beta-chain. Additional autophosphorylation sites such as tyrosine residue 950 and 1316 regulate the assembly of signal transduction complexes.Synonyms: IGF-I receptor, IGF1 Receptor, Insulin-like growth factor 1 receptor

    分子量

    97 kDa

    基因ID

    3480

    UniProt

    P08069

    途径

    RTK signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagy
You are here:
Chat with us!