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IGF1R 抗体 (C-Term) (Biotin)

IGF1R 适用: 人 WB 宿主: 小鼠 Monoclonal 7G11 Biotin
产品编号 ABIN126814
发货至: 中国
  • 抗原 See all IGF1R 抗体
    IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))
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    C-Term
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This IGF1R antibody is conjugated to Biotin
    应用范围
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    Western Blotting (WB)
    特异性
    This antibody specifically recognizes the C-terminus of IGF1 Receptor.
    产品特性
    Synonyms: IGF-I receptor, IGF1 Receptor, Insulin-like growth factor 1 receptor
    纯化方法
    Subsequent Thiophilic Adsorption and Size Exclusion Chromatography
    组件
    incl. positive Control
    免疫原
    Synthetic peptide conjugated to KLH. Remarks: Mol. Weight: 97 kDa
    克隆位点
    7G11
    亚型
    IgG1
    Top Product
    Discover our top product IGF1R Primary Antibody
  • 应用备注
    Western Blot: 0.5 μg/mL for HRPO/ECL detection. Recommended blocking buffer: Casein/Tween 20 based blocking and blot incubationbuffer. Positive Control: Cell lysate from untreated A431 cells (See Protocols for more details).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    实验流程
    Positive Control Cell Lysate A431 Untreated
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    PBS, 0.09 % Sodium Azide, PEG and Sucrose
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-80 °C
    储存方法
    Store the antibody (aliquote in liquid nitrogen) at -80 °C. Avoid repeated freezing and thawing. Thaw aliquots at 37 °C. Thawed aliquots may be stored at 4 °C up to 3 months.
    Shelf life: one year from despatch.
    有效期
    12 months
  • 抗原
    IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))
    别名
    CD221 / IGF1R (IGF1R 产品)
    别名
    CMT2N antibody, CD221 antibody, IGFIR antibody, IGFR antibody, JTK13 antibody, IGFIRC antibody, IGFR1 antibody, IGF-1R antibody, IGF1R antibody, DKFZp469I0618 antibody, igf-1r antibody, xIGF-1R antibody, xIGFR antibody, xigf1r antibody, A330103N21Rik antibody, D930020L01 antibody, hyft antibody, igf-ir antibody, IGF-IR antibody, IGF-IRb antibody, wu:fb03h06 antibody, IGF-IRa antibody, sb:eu1090 antibody, wu:fi20b10 antibody, alanyl-tRNA synthetase antibody, insulin like growth factor 1 receptor antibody, insulin-like growth factor 1 receptor antibody, insulin-like growth factor 1 antibody, insulin-like growth factor I receptor antibody, insulin like growth factor 1 receptor S homeolog antibody, insulin-like growth factor 1b receptor antibody, insulin-like growth factor 1a receptor antibody, AARS antibody, IGF1R antibody, Igf1r antibody, igf1r antibody, Igf1 antibody, LOC780503 antibody, LOC100136427 antibody, igf1r.S antibody, igf1rb antibody, igf1ra antibody
    背景
    The IGF1 receptor (IGF1R) is a heterodimeric receptor tyrosine kinase with an extracellular alpha-chain, a transmembrane domain and an intracellular beta-chain. The IGF1 receptor is activated upon binding of the peptide hormones IGF1 and 2, leading to autophosphorylation of tyrosine residue 1131, 1135, and 1136 in the activation loop of the beta-chain. Additional autophosphorylation sites such as tyrosine residue 950 and 1316 regulate the assembly of signal transduction complexes.Synonyms: IGF-I receptor, IGF1 Receptor, Insulin-like growth factor 1 receptor
    分子量
    97 kDa
    基因ID
    3480
    UniProt
    P08069
    途径
    RTK signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagy
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