IGF1R 抗体 (pTyr1316)
Quick Overview for IGF1R 抗体 (pTyr1316) (ABIN126813)
抗原
See all IGF1R 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- pTyr1316
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特异性
- This antibody specifically recognizes the IGF1 receptor phosphorylated at tyrosine 1316.
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产品特性
- Synonyms: IGF-I receptor, IGF1 Receptor, Insulin-like growth factor 1 receptor
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纯化方法
- Size exclusion chromatography
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组件
- incl. positive Control
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免疫原
- Synthetic phosphopeptide conjugated to KLH.
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亚型
- IgG1
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anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 251-350) antibody
IGF1R 适用: 人, 小鼠, 大鼠, 犬 FACS 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (pTyr1346) antibodyIGF1R 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (pTyr1161) antibodyIGF1R 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (pTyr1165), (pTyr1166) antibodyIGF1R 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 51-77) antibodyIGF1R 适用: 人 WB, IHC, ELISA, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 1335-1366), (C-Term) antibodyIGF1R 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB01458 unconjugated
anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (C-Term) antibodyIGF1R 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 660-760) antibodyIGF1R 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (pTyr980) antibodyIGF1R 适用: 人, 小鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 763-955) antibodyIGF1R 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot: 1 μg/mL for HRPO/ECL detection. Recommended blocking buffer: Casein/Tween 20 based blocking and blot incubationbuffer. Positive Control: Cell lysate from Insulin-treated HEK-293 cells. ELISA: 0.1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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溶解方式
- Restore with 1 mL H2O (15 min, RT).
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缓冲液
- 1 mL2 x PBS / 0.09 % Na-azide / PEG and Sucrose
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C/-80 °C
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储存方法
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Store lyophilized (preferably in a desiccator) at -20 °C and reconstituted (aliquote andfreeze in liquid nitrogen) at -80 °C. Avoid repeated freezing and thawing. Thaw aliquots at 37 °C. Thawed aliquots may be stored at 4 °C up to 3 months.
Shelf life: one year from despatch. -
有效期
- 12 months
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- IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))
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别名
- CD221 / IGF1R
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背景
- The IGF1 receptor (IGF1R) is a heterodimeric receptor tyrosine kinase with an extracellular alpha-chain, a transmembrane domain and an intracellular beta-chain. The IGF1 receptor is activated upon binding of the peptide hormones IGF1 and IGF2, leading to autophosphorylation of tyrosine residues 1131, 1135, and 1136 in the activation loop of the beta-chain. Additional autophosphorylation sites such as tyrosine residues 950 and 1316 regulate the assembly of signal tranduction complexes.Synonyms: IGF-I receptor, IGF1 Receptor, Insulin-like growth factor 1 receptor
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基因ID
- 3480
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UniProt
- P08069
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途径
- RTK signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagy
抗原
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