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CD14 抗体 (PE)

This anti-CD14 antibody is a 小鼠 单克隆 antibody detecting CD14 in FACS. Suitable for 人.
产品编号 ABIN120780
发货至: 中国

Quick Overview for CD14 抗体 (PE) (ABIN120780)

抗原

See all CD14 抗体
CD14

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD14 antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS)

克隆位点

MEM-15
  • 纯化方法

    Size-exclusion chromatography

    免疫原

    A crude mixture of human urinary proteins precipitated by ammonium sulphate from the urine of a patient suffering from proteinuria

    亚型

    IgG1
  • 应用备注

    Flow cytometry analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 10^6 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 15 mM sodium azide and 0.2 % (w/v) high-grade protease free BSA as a stabilizing agent

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
    Shelf Life: one year from despatch.

    有效期

    12 months
  • 抗原

    CD14

    别名

    CD14

    背景

    CD14 is a 55 kDa GPI-anchored glycoprotein, constitutively expressed on the surface of mature monocytes, macrophages, and neutrophils, where it serves as a multifunctional lipopolysaccharide receptor, it is also released to the serum both as a secreted and enzymatically cleaved GPI-anchored form. CD14 binds lipopolysaccharide molecule in a reaction catalyzed by lipopolysaccharide-binding protein (LBP), an acute phase serum protein. The soluble sCD14 is able to discriminate slight structural differences between lipopolysaccharides and is important for neutralization of serum allochthonous lipopolysaccharides by reconstituted lipoprotein particles. CD14 affects allergic, inflammatory and infectious processes.Synonyms: Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein

    UniProt

    P08571

    途径

    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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