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TNFSF18 抗体

TNFSF18 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal YGL386 unconjugated
产品编号 ABIN120289
发货至: 中国
  • 抗原 See all TNFSF18 抗体
    TNFSF18 (Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18))
    适用
    • 61
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    小鼠
    宿主
    • 52
    • 10
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    大鼠
    克隆类型
    • 51
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    单克隆
    标记
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    This TNFSF18 antibody is un-conjugated
    应用范围
    • 54
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    Flow Cytometry (FACS)
    纯化方法
    Affinity chromatography on Protein G
    免疫原
    Recombinant mouse GITRL. Spleen cells from immunised DA rats were fused with cells of the Y3/Ag1.2.3 myeloma cell line.
    克隆位点
    YGL386
    亚型
    IgG1
    Top Product
    Discover our top product TNFSF18 Primary Antibody
  • 应用备注
    Flow Cytometry: 1/25 - 1/50, use 10 μL of the suggested working dilution to label 106 cells in 100 μL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS, pH 7.4 containing 0.09 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    TNFSF18 (Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18))
    别名
    TNFSF18 / AITRL (TNFSF18 产品)
    别名
    Gitrl antibody, AITRL antibody, GITRL antibody, TL6 antibody, hGITRL antibody, TNLG2A antibody, tumor necrosis factor (ligand) superfamily, member 18 antibody, TNF superfamily member 18 antibody, Tnfsf18 antibody, TNFSF18 antibody
    背景
    GITRL is a 20 kD member of the tumour necrosis factor ligand superfamily, otherwise known as TNSF18. Mouse GITRL is predominantly expressed on immature and mature dendritic cells, macrophages and B cells. Expression of mouse GITRL can be transiently up regulated on these cells, following lipolysaccharide (LPS) stimulation, but protein expression is rapidly down modulated shortly after stimulation. Studies demonstrate that GITRL can neutralise the suppressive effects of CD4+CD25+ regulatory T cells and can also provide a co-stimulatory signal for both naive and primed T cells, suggesting a key role for GITRL in the regulation of T cell-mediated immunity.Synonyms: AITRL, Activation-inducible TNF-related ligand, GITRL, Glucocorticoid-induced TNF-related ligand, TL6, Tumor necrosis factor ligand superfamily member 18, hGITRL
    基因ID
    10090
    UniProt
    Q7TS55
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