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CD58 抗体

CD58 适用: 人 FACS, WB 宿主: 小鼠 Monoclonal BRIC-5 unconjugated
产品编号 ABIN118746
发货至: 中国
  • 抗原 See all CD58 抗体
    CD58
    适用
    • 73
    • 5
    • 3
    • 2
    宿主
    • 37
    • 36
    小鼠
    克隆类型
    • 37
    • 36
    单克隆
    标记
    • 29
    • 7
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    • 5
    • 5
    • 2
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    • 2
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    • 1
    • 1
    • 1
    • 1
    • 1
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    This CD58 antibody is un-conjugated
    应用范围
    • 40
    • 33
    • 13
    • 13
    • 10
    • 7
    • 7
    • 6
    • 5
    • 4
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    Flow Cytometry (FACS), Western Blotting (WB)
    特异性
    BRIC5 was produced in response to erythrocytes. It reacts by Immunoblotting to non-reduced erythrocyte membranes. BRIC5 is an indirect haemagglutinin. The antigen on erythrocytes is Pronase sensitive. BRIC5 inhibits T cell rosetting.Aff. Const.:4 x 10e8 M-1
    纯化方法
    Affinity Chromatography on Protein G.
    免疫原
    Human erythrocytes.
    克隆位点
    BRIC-5
    亚型
    IgG2a
    Top Product
    Discover our top product CD58 Primary Antibody
  • 应用备注
    Flow Cytometry: Use 10 μL of 1/10 diluted antibody to label 10^6 cells in 100 μL. Western Blot.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    CD58
    别名
    CD58 / LFA3 (CD58 产品)
    别名
    LFA-3 antibody, LFA3 antibody, ag3 antibody, CD58 molecule antibody, CD58 antibody
    背景
    CD58, or LFA-3, is a membrane glycoprotein of 55-70kD. It occurs in two forms, one transmembrane with a cytoplasmic domain, the other form anchored in the membrane via a glycosylphosphatidylinositol tail. The complete amino acid sequence of both forms has been deduced from cDNA. It is heavily N-glycosylated. CD58 is a cell adhesion molecule which plays a critical role in facilitation of antigen specific recognition through interaction with CD2 on T lymphocytes. It is a member of the immunoglobulin superfamily of molecules. CD58 has a wide tissue distribution, being present on erythrocytes, platelets, monocytes, a subset of lymphocytes, bone marrow cells, epithelium and endothelial cells. There are approximately 5,000 CD58 Molecules on each erythrocyte. There is reduced expression of CD58 on haemopoietic cells in individuals with paroxysmal nocturnal haemoglobinuria.Synonyms: Ag3, LFA-3, Lymphocyte function-associated antigen 3
    基因ID
    965
    NCBI登录号
    NP_001138294
    UniProt
    P19256
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