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CD56 抗体

NCAM1 适用: 人, Pig FACS, WB, IHC (fro) 宿主: 小鼠 Monoclonal ERIC-1 unconjugated
产品编号 ABIN118740
发货至: 中国
  • 抗原 See all CD56 (NCAM1) 抗体
    CD56 (NCAM1) (Neural Cell Adhesion Molecule 1 (NCAM1))
    适用
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    人, Pig
    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CD56 antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    This antibody recognises N-CAM expressed on developing and adult neuroectodermal tissues. Neuroectodermal tumours also stain including Glioma, ependymoma, neuroblastoma, medulloblastoma, retinoblastoma and teratoma. Oat cell carcinoma and Wilms tumour are also highly reactive. ERIC-1 will react on Natural Killer cells and recognises 180, 140 and 120 kDa NCAM isoforms.
    纯化方法
    Affinity Chromatography on Protein A
    免疫原
    Human Retinoblastoma tumour. Remarks: Spleen cells from immunised BALB/c mice were fused with cells of the P3/X63.Ag8 mouse myeloma line.
    克隆位点
    ERIC-1
    亚型
    IgG1
    Top Product
    Discover our top product NCAM1 Primary Antibody
  • 应用备注
    Immunohistochemistry on frozen sections. Western Blot. ELISA: 80 ng/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS without preservatives
    储存液
    Without preservative
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
  • 抗原
    CD56 (NCAM1) (Neural Cell Adhesion Molecule 1 (NCAM1))
    别名
    CD56 (NCAM1 产品)
    别名
    CD56 antibody, MSK39 antibody, NCAM antibody, fj56g09 antibody, ncam antibody, ncam1 antibody, wu:fj56g09 antibody, NCAM1 antibody, n-cam antibody, E-NCAM antibody, NCAM-1 antibody, Ncam antibody, Cd56 antibody, N-CAM antibody, N-CAM-1 antibody, NCAM-C antibody, NCAMC antibody, N-CAM-1-B antibody, NCAM-1-B antibody, ncam1-a antibody, ncam1-b antibody, neural cell adhesion molecule 1 antibody, neural cell adhesion molecule 1a antibody, neural cell adhesion molecule 1 S homeolog antibody, neural cell adhesion molecule 1 L homeolog antibody, NCAM1 antibody, ncam1a antibody, ncam1 antibody, LOC100085373 antibody, ncam1.S antibody, Ncam1 antibody, ncam1.L antibody
    背景
    NCAM, as a member of the immunoglobulin superfamily of adhesion molecules is characterized by several immunoglobulin (Ig) like domains. The extracellular part of NCAM consists of five of these Ig domains and two fibronectin type III homology regions. NCAM is encoded by a single copy gene composed of 26 exons. However, at least 20-30 distinct isoforms can be generated by alternative splicing and by posttranslational modifications, such as sialylation. During sialylation, polysialic acid (PSA) carbohydrates are attached to the extracellular part of NCAM. Through its extracellular region, NCAM mediates homophilic interactions. In addition, NCAM can also undergo heterophilic interactions by binding extracellular matrix components, such as laminin, or other cell adhesion molecules, such as integrins. NCAM is expressed on most neuroectodermal derived cell lines, tissues and neoplasm such as retinoblastoma, medulloblastoma, astrocytomas and neuroblastoma.Synonyms: N-CAM-1, NCAM, NCAM-1, Neural cell adhesion molecule 1
    基因ID
    4684
    NCBI登录号
    NP_000606
    UniProt
    P13591
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