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- 抗原 See all SUMO3 抗体
- SUMO3 (Small Ubiquitin Related Modifier 3 (SUMO3))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SUMO3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 特异性
- Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Rabbit Serum.
- 交叉反应 （详细）
- Species reactivity (tested):Human
- 纯化方法
- Multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis
- 免疫原
- This purified antibody was prepared from rabbit serum after repeated immunizations with recombinant human SUMO-3 protein.
- Top Product
- Discover our top product SUMO3 Primary Antibody
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anti-Small Ubiquitin Related Modifier 3 (SUMO3) (AA 1-103) antibody
SUMO3 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Small Ubiquitin Related Modifier 3 (SUMO3) (AA 1-103) antibodySUMO3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4G11 unconjugated
anti-Small Ubiquitin Related Modifier 3 (SUMO3) (AA 1-92) antibodySUMO3 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Small Ubiquitin Related Modifier 3 (SUMO3) (AA 1-103) antibodySUMO3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4B9 unconjugated
anti-Small Ubiquitin Related Modifier 3 (SUMO3) (AA 1-92) antibodySUMO3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Small Ubiquitin Related Modifier 3 (SUMO3) (N-Term) antibodySUMO3 适用: 人, 小鼠, 大鼠, Cow, 兔, 斑马鱼, 豚鼠, 马, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Small Ubiquitin Related Modifier 3 (SUMO3) (C-Term) antibodySUMO3 适用: 人, 小鼠 WB, EIA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Small Ubiquitin Related Modifier 3 (SUMO3) (AA 1-103) antibodySUMO3 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Small Ubiquitin Related Modifier 3 (SUMO3) (AA 6-55) antibodySUMO3 适用: 人, 小鼠, 大鼠, Cow, 兔, 斑马鱼, 小鸡, Pig, 豚鼠, 马, Bat, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Small Ubiquitin Related Modifier 3 (SUMO3) antibodySUMO3 适用: 人 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA. Western blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 溶解方式
- Restore with 0.1 mL of deionized water (or equivalent).
- 浓度
- 5.0 mg/mL (by UV absorbance at 280 nm)
- 缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide as preservative.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing. Dilute only prior to immediate use
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store vial at 2-8 °C prior to restoration. For extended storage mix with glycerol to 50% and then aliquot contents and freeze at -20 °C or below. Centrifuge product if not completely clear after standing at room temperature. This product is stable for one month at 2-8 °C as an undiluted liquid.
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- 抗原
- SUMO3 (Small Ubiquitin Related Modifier 3 (SUMO3))
- 别名
- SUMO3 / SMT3A (SUMO3 产品)
- 别名
- SMT3A antibody, SMT3H1 antibody, SUMO-3 antibody, Smt3B antibody, 2810014B19Rik antibody, AA409334 antibody, AW121497 antibody, AW536077 antibody, D10Ertd345e antibody, Smt3h1 antibody, smt3a antibody, smt3h1 antibody, fa94a11 antibody, im:7141764 antibody, sumo2 antibody, sumo3 antibody, sumo3l antibody, wu:fa94a11 antibody, wu:fb55d09 antibody, zgc:65847 antibody, zgc:85643 antibody, fc66f10 antibody, fl11h12 antibody, wu:fc66f10 antibody, wu:fl11h12 antibody, zgc:86902 antibody, SUMO3 antibody, ATSUMO3 antibody, MCO15.12 antibody, MCO15_12 antibody, SMALL UBIQUITIN-LIKE MODIFIER 3 antibody, SUM3 antibody, SUMO 3 antibody, small ubiquitin-like modifier 3 antibody, GMP1 antibody, PIC1 antibody, SENTRIN antibody, SMT3 antibody, SMT3H3 antibody, SMTP3 antibody, SUMO-1 antibody, Smt3C antibody, Ubl1 antibody, small ubiquitin-like modifier 3 antibody, small ubiquitin-like modifier 3 L homeolog antibody, small ubiquitin-like modifier 3a antibody, small ubiquitin-like modifier 3b antibody, small ubiquitin-related modifier 2 pseudogene antibody, SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae) antibody, small ubiquitin-like modifier 2 antibody, small ubiquitin-like modifier 1 antibody, SUMO3 antibody, Sumo3 antibody, sumo3.L antibody, sumo3a antibody, sumo3b antibody, LOC490297 antibody, sumo3 antibody, sumo2 antibody, Sumo1 antibody
- 背景
- Covalent modification of cellular proteins by the ubiquitin-like modifier SUMO (small ubiquitin-like modifier) regulates various cellular processes, such as nuclear transport, signal transduction, stress responses and cell cycle progression. But, in contrast to ubiquination, sumoylation does not tag proteins for degradation by the 26S proteasome, but rather seems to enhance stability or modulate their subcellular compartmentalization. Ubiquitin-like proteins fall into two classes: the first class, ubiquitin-like modifiers (UBLs) function as modifiers in a manner analogous to that of ubiquitin. Examples of UBLs are SUMO, Rub1 (also called Nedd8), Apg8 and Apg12. Proteins of the second class include parkin, RAD23 and DSK2, are designated ubiquitin-domain proteins (UDPs). These proteins contain domains that are related to ubiquitin but are otherwise unrelated to each other. In contrast to UBLs, UDPs are not conjugated to other proteins. Once covalently attached to cellular targets, SUMO regulates protein:protein and protein:DNA interactions, as well as localization and stability of the target protein. Sumoylation occurs in most eukaryotic systems, and SUMO is highly conserved from yeast to human. Where invertebrates have only a single SUMO gene termed SMT3, three members of the SUMO family have been identified in vertebrates: SUMO-1 and the close homologues SUMO-2 and SUMO-3. SUMO has been called SMT3 (yeast), sentrin, PIC1, GMP1 and UBL1. SUMO has been shown to bind and regulate mammalian SP-RINGs (such as Mdm2, PIAS and PML), RanGAP1, RanBP2, p53, p73, HIPK2, TEL, c- Jun, Fas, Daxx, TNFRI, Topo-I, Topo-II, WRN, Sp100, IκB-α, Androgen receptor (AR), GLUT1/4, Drosophila Ttk69, Dorsal, CaMK, yeast Septins, and viral CMV-IE1/2, EBV-BZLF1, HPV/BPV-E1. These bindings implicate SUMO in the stabilization of the target proteins and/or their localization to subcellular complexes. SUMO has an apparent molecular weight of ~12 kDa and human SUMO-1 (a 101 amino acid polypeptide) shares 50 % sequence identity with SUMO-2 and SUMO-3 and with yeast SMT3. SUMO and ubiquitin only show about 18 % homology, but both possess a common three-dimensional structure characterized by a tightly packed globular fold with β-sheets wrapped around an α-helix.Synonyms: SMT3 homolog 1, SMT3H1, SUMO-3, Small ubiquitin-related modifier 3, Ubiquitin-like protein SMT3A
- 基因ID
- 6612
- NCBI登录号
- NP_008867
- UniProt
- P55854
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