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CD47 抗体

CD47 适用: 人 FACS 宿主: 小鼠 Monoclonal B6H12 unconjugated
产品编号 ABIN1177375
发货至: 中国
  • 抗原 See all CD47 抗体
    CD47
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CD47 antibody is un-conjugated
    应用范围
    • 83
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    Flow Cytometry (FACS)
    品牌
    BD Pharmingen™
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    过滤
    0.2 μm filtered
    内毒素水平
    Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.
    克隆位点
    B6H12
    亚型
    IgG1 kappa
    Top Product
    Discover our top product CD47 Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.0 mg/mL
    缓冲液
    No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.
    储存液
    Azide free
    储存条件
    4 °C
    储存方法
    Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
  • Lindberg, Lublin, Telen, Veile, Miller, Donis-Keller, Brown: "Rh-related antigen CD47 is the signal-transducer integrin-associated protein." in: The Journal of biological chemistry, Vol. 269, Issue 3, pp. 1567-70, (1994) (PubMed).

    Brown, Hooper, Ho, Gresham: "Integrin-associated protein: a 50-kD plasma membrane antigen physically and functionally associated with integrins." in: The Journal of cell biology, Vol. 111, Issue 6 Pt 1, pp. 2785-94, (1991) (PubMed).

  • 抗原
    CD47
    别名
    CD47 (IAP) (CD47 产品)
    别名
    IAP antibody, MER6 antibody, OA3 antibody, 9130415E20Rik antibody, AA407862 antibody, AI848868 antibody, AW108519 antibody, B430305P08Rik antibody, Itgp antibody, CD47/IAP antibody, alkaline phosphatase, intestinal antibody, CD47 molecule antibody, CD47 antigen (Rh-related antigen, integrin-associated signal transducer) antibody, Cd47 molecule antibody, ALPI antibody, CD47 antibody, Cd47 antibody
    背景
    The B6H12 monoclonal antibody specifically binds to a 42-52 kDa N-linked glycan protein. CD47 antigen, also known as integrin-associated protein (IAP), is expressed on all hematopoietic cells, including leukocytes, platelets and erythrocytes. It is also expressed on epithelial cells, endothelial cells, fibroblasts and many tumor cell lines. CD47 may play a role as a signal transducer in the regulation of cation fluxes across cell membranes and in the chemotactic and adhesive interactions of leukocytes with endothelial cells. The B6H12 antibody is capable of blocking phagocytosis of microparticles by peripheral blood granulocytes. It has also been reported to induce proliferation of CD3-activated T cells.
    Synonyms: IAP, CDw149, gp42, MER6, Neurophilin, OA3 , Rh-related antigen
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