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Fc gamma RII (CD32) 抗体

CD32 适用: 人 FACS 宿主: 小鼠 Monoclonal 3D3 unconjugated
产品编号 ABIN1177311
发货至: 中国
  • 抗原 See all Fc gamma RII (CD32) 抗体
    Fc gamma RII (CD32)
    适用
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    宿主
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    • 62
    小鼠
    克隆类型
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    单克隆
    标记
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    非结合性
    应用范围
    • 71
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    Flow Cytometry (FACS)
    品牌
    BD Pharmingen™
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    过滤
    0.2 μm filtered
    内毒素水平
    Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.
    克隆位点
    3D3
    亚型
    IgG1 kappa
    Top Product
    Discover our top product CD32 Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.0 mg/mL
    缓冲液
    No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.
    储存液
    Azide free
    储存条件
    4 °C
    储存方法
    Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
  • Vely, Gruel, Moncuit, Cochet, Rouard, Dare, Galon, Sautes, Fridman, Teillaud: "A new set of monoclonal antibodies against human Fc gamma RII (CD32) and Fc gamma RIII (CD16): characterization and use in various assays." in: Hybridoma, Vol. 16, Issue 6, pp. 519-28, (1998) (PubMed).

    Gosselin, Brown, Anderson, Zipf, Guyre: "The monoclonal antibody 41H16 detects the Leu 4 responder form of human Fc gamma RII." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 144, Issue 5, pp. 1817-22, (1990) (PubMed).

  • 抗原
    Fc gamma RII (CD32)
    别名
    CD32 (CD32 产品)
    别名
    CD32 antibody, CD32B antibody, FCG2 antibody, FCGR2 antibody, IGFR2 antibody, FCGR2B antibody, AI528646 antibody, F630109E10Rik antibody, Fc[g]RII antibody, FcgRII antibody, Fcgr2 antibody, Fcgr2a antibody, Fcr-2 antibody, Fcr-3 antibody, Ly-17 antibody, Ly-m20 antibody, LyM-1 antibody, Lym-1 antibody, FCRII antibody, FcRII antibody, Fc fragment of IgG receptor IIb antibody, Fc receptor, IgG, low affinity IIb antibody, FCGR2B antibody, Fcgr2b antibody
    背景
    Reacts with FcgammaRII (CD32), a 40 kDa, polymorphic transmembranous glycoprotein, highly glycosylated molecule (encoded by at least two genes), expressed on monocytes, granulocytes, platelets and B cells. Unlike FLI28.6, 3D3 mAb detected a polymorphic CD32 antigen expressed on B cells of all donors, but only on platelets, monocytes and granulocytes of some donors. The platelets from 3D3+ donors respond to certain stimulatory mAb such as CD165 (clone SN2, Cat. No. 556050) and result in aggregation. On the other hand, the platelets from 3D3 negative donors do not form aggregates after stimulation. Individuals can be divided into two groups as responder and non-responder depending on expression, or non-expression, of 3D3. In comparison to 3D3, FLI8.26 detects a monomorphic CD32 antigen expressed on all human donors.
    Synonyms: FcgammaRII
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