10ng/mL Prednisolone produces 59% inhibition in a competitive ELISA employing Prednisolone polyclonal Antibody
产品特性
Polyclonal High sensitivity High concentration Excellent specificity to target compound Detailed cross reactivity profiles Available for bulk purchase Stable when stored at -20 °C Excellent reproducibility between lot numbers Matching conjugates available
The antibody is suitable for the development of immunoassays or immunoaffinity purification columns.
限制
仅限研究用
状态
Liquid
浓度
15.88 mg/mL
缓冲液
20 mM Phosphate, 150 mM Sodium Chloride
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
抗原
Prednisolone
物质类
Hormone
背景
Dehydroepiandrosterone is the most abundant adrenal androgen in humans and exists predominately in a sulfated form (DHEAS) [1]. DHEA sulfotransferase, known as SULT2A1, converts the androgen precursor DHEA to its inactive sulfate ester, DHEAS. The unconjugated molecules can be converted directly to androgens. Dehydroepiandrosterone is converted to DHEAS in the adrenal glands and liver [2]. DHEA in adults is present at plasma concentrations 100 to 500 times higher than those of testosterone. DHEA can be metabolized to androgens and/or estrogens in the prostate [3]. Hepatic metabolites include 16alpha-hydroxy-DHEA, 7alpha-hydroxy-DHEA, and 7-oxo-DHEA [4]. 7beta-OH-DHEA is a metabolite [5]. The major metabolite produced in humans is a mono-hydroxylated DHEA species [4]. Synthesis of a 7alpha-hydroxy-DHEA and 5-androstene-3beta, 17beta-diol occurs in the frontal cortex, hippocampus, aμgdala, cerebellum and striatum [6].