-
- 抗原 See all FNDC5 抗体
- FNDC5 (Fibronectin Type III Domain Containing 5 (FNDC5))
-
适用
- 人, 小鼠, 大鼠, 猴
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This FNDC5 antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 特异性
- Recognizes human, mouse, rat, monkey Irisin and FNDC5. Detects endogenous mouse and human Irisin [Lit: 1-2].
- 交叉反应
- 人, 猴, 小鼠, 大鼠
- 免疫原
- Recombinant irisin.
- Top Product
- Discover our top product FNDC5 Primary Antibody
-
-
- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- In PBS containing 10 % glycerol and 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
-
Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. - 有效期
- 12 months
-
-
Exercise induces hippocampal BDNF through a PGC-1α/FNDC5 pathway." in: Cell metabolism, Vol. 18, Issue 5, pp. 649-59, (2013) (PubMed).
: "
-
Exercise induces hippocampal BDNF through a PGC-1α/FNDC5 pathway." in: Cell metabolism, Vol. 18, Issue 5, pp. 649-59, (2013) (PubMed).
-
- 抗原
- FNDC5 (Fibronectin Type III Domain Containing 5 (FNDC5))
- 别名
- Irisin (FNDC5 产品)
- 别名
- FRCP2 antibody, irisin antibody, 1500001L03Rik antibody, AI836596 antibody, C87088 antibody, PeP antibody, Pxp antibody, fndc5 antibody, si:dkey-264p5.1 antibody, zgc:158684 antibody, fibronectin type III domain containing 5 antibody, fibronectin type III domain containing 5b antibody, FNDC5 antibody, Fndc5 antibody, fndc5b antibody
- 背景
- Irisin is a recently described exercise-induced hormone secreted by skeletal muscle in mice and humans. Irisin activates beige fat cells (beige cells have a gene expression pattern distinct from either white or brown fat and are preferentially sensitive to the polypeptide hormone Irisin). Irisin is cleaved from the type I membrane protein FNDC5 and improves systemic metabolism by increasing energy expenditure.
- UniProt
- Q8NAU1
- 途径
- Hormone Activity, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
-