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FNDC5 抗体

FNDC5 适用: 人, 小鼠, 大鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1169430
发货至: 中国
  • 抗原 See all FNDC5 抗体
    FNDC5 (Fibronectin Type III Domain Containing 5 (FNDC5))
    适用
    • 44
    • 31
    • 28
    • 4
    • 4
    • 1
    人, 小鼠, 大鼠, 猴
    宿主
    • 43
    • 2
    克隆类型
    • 42
    • 3
    多克隆
    标记
    • 17
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    This FNDC5 antibody is un-conjugated
    应用范围
    • 41
    • 17
    • 13
    • 13
    • 10
    • 8
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    特异性
    Recognizes human, mouse, rat, monkey Irisin and FNDC5. Detects endogenous mouse and human Irisin [Lit: 1-2].
    交叉反应
    人, 猴, 小鼠, 大鼠
    免疫原
    Recombinant irisin.
    Top Product
    Discover our top product FNDC5 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    In PBS containing 10 % glycerol and 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 1 year after receipt when stored at -20°C.
    有效期
    12 months
  • Wrann, White, Salogiannnis, Laznik-Bogoslavski, Wu, Ma, Lin, Greenberg, Spiegelman: "Exercise induces hippocampal BDNF through a PGC-1α/FNDC5 pathway." in: Cell metabolism, Vol. 18, Issue 5, pp. 649-59, (2013) (PubMed).

  • 抗原
    FNDC5 (Fibronectin Type III Domain Containing 5 (FNDC5))
    别名
    Irisin (FNDC5 产品)
    别名
    FRCP2 antibody, irisin antibody, 1500001L03Rik antibody, AI836596 antibody, C87088 antibody, PeP antibody, Pxp antibody, fndc5 antibody, si:dkey-264p5.1 antibody, zgc:158684 antibody, fibronectin type III domain containing 5 antibody, fibronectin type III domain containing 5b antibody, FNDC5 antibody, Fndc5 antibody, fndc5b antibody
    背景
    Irisin is a recently described exercise-induced hormone secreted by skeletal muscle in mice and humans. Irisin activates beige fat cells (beige cells have a gene expression pattern distinct from either white or brown fat and are preferentially sensitive to the polypeptide hormone Irisin). Irisin is cleaved from the type I membrane protein FNDC5 and improves systemic metabolism by increasing energy expenditure.
    UniProt
    Q8NAU1
    途径
    Hormone Activity, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
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