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- 抗原 See all NLRP1 抗体
- NLRP1 (NLR Family, Pyrin Domain Containing 1 (NLRP1))
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抗原表位
- AA 2-25, N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NLRP1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- Recognizes human NLRP1/NALP1.
- 交叉反应
- 人
- 无交叉反应
- 小鼠
- 交叉反应 （详细）
- Does not cross-react with mouse NLRP1/NALP1.
- 免疫原
- Synthetic peptide corresponding to aa 2-25 (A2GGAWGRLACYLEFLKKEELKEFQ25) at the N-terminus of human NLRP1/NALP1.
- Top Product
- Discover our top product NLRP1 Primary Antibody
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anti-NLR Family, Pyrin Domain Containing 1 (NLRP1) (AA 1000-1100) antibody
NLRP1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 1 (NLRP1) (AA 589-655) antibodyNLRP1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 1 (NLRP1) (AA 323-372) antibodyNLRP1 适用: 人, 小鼠, Cow, 犬, 马, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 1 (NLRP1) (C-Term) antibodyNLRP1 适用: 人 WB, IHC, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 1 (NLRP1) antibodyNLRP1 适用: 人 IHC (p), IHC (fro), IP 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 1 (NLRP1) antibodyNLRP1 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 1 (NLRP1) (AA 1-146) antibodyNLRP1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 1 (NLRP1) (AA 1-1429) antibodyNLRP1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 1 (NLRP1) (N-Term) antibodyNLRP1 适用: 人, 小鼠, Cow, 犬, 马, 大鼠, 豚鼠, Pig, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 1 (NLRP1) (C-Term) antibodyNLRP1 适用: 人 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- In PBS containing 10 % glycerol and 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. - 有效期
- 12 months
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- 抗原
- NLRP1 (NLR Family, Pyrin Domain Containing 1 (NLRP1))
- 别名
- NLRP1/NALP1 (NLRP1 产品)
- 别名
- CARD7 antibody, CIDED antibody, CLR17.1 antibody, DEFCAP antibody, DEFCAP-L/S antibody, NAC antibody, NALP1 antibody, PP1044 antibody, SLEV1 antibody, VAMAS1 antibody, NLR family pyrin domain containing 1 antibody, NLRP1 antibody, Nlrp1 antibody
- 背景
- NALP1/NLRP1 is able to form cytoplasmic structures termed death effector filaments. It enhances and stimulates apoptosis through activation of different caspase cascades. It is involved in the activation of caspase-1 and caspase-5 as part of the NALP1 inflammasome complex which leads to processing and release of IL1B and IL18. Genetic variations in the NLRP1/NALP1 gene are associated with susceptibility to vitiligo-associated multiple autoimmune disease type 1, an autoimmune disorder characterized by the association of vitiligo with several autoimmune and autoinflammatory diseases including autoimmune thyroid disease, rheumatoid arthritis and systemic lupus erythematosus.
- UniProt
- Q9C000
- 途径
- Positive Regulation of Endopeptidase Activity, Inflammasome
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