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IL1A 抗体

IL1A 适用: 小鼠 WB, ELISA 宿主: 小鼠 Monoclonal Bamboo-1 unconjugated
产品编号 ABIN1169127
发货至: 中国
  • 抗原 See all IL1A 抗体
    IL1A (Interleukin 1 alpha (IL1A))
    适用
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    小鼠
    宿主
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    小鼠
    克隆类型
    • 158
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    单克隆
    标记
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    This IL1A antibody is un-conjugated
    应用范围
    • 146
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    Western Blotting (WB), ELISA
    特异性
    Recognizes mouse IL-1alpha.
    交叉反应
    小鼠
    纯化方法
    Purified from concentrated hybridoma tissue culture supernatant.
    纯度
    >95 % (SDS-PAGE)
    免疫原
    Recombinant mouse mature IL-1alpha.
    克隆位点
    Bamboo-1
    亚型
    IgG
    Top Product
    Discover our top product IL1A Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    In PBS containing 10 % glycerol and 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 1 year after receipt when stored at -20°C.
    有效期
    12 months
  • 抗原
    IL1A (Interleukin 1 alpha (IL1A))
    别名
    IL-1alpha (IL1A 产品)
    别名
    IL-1A antibody, IL1 antibody, IL1-ALPHA antibody, IL1F1 antibody, IL-6 antibody, Il-1a antibody, IL-1 alpha antibody, IL-1alpha antibody, L1A antibody, interleukin 1 alpha antibody, interleukin 6 antibody, IL1A antibody, IL6 antibody, Il1a antibody
    背景
    The most prominent members of the interleukin-1 (IL-1) superfamily are IL-1alpha and IL-1beta. They lack a signal peptide and are secreted by an unconventional, endoplasmic reticulum-Golgi-independent mechanism. IL-1alpha was reported to be more widely and constitutively expressed and has intracellular functions, but also acts locally in a membrane-bound form by activating IL-1R1. Additionally, passive release of IL-1alpha upon cell death can trigger a sterile inflammatory response to dying cells. The cleavage of IL-1alpha is not mediated by caspase-1 and is not required for binding to IL-1R1. Recently it has been observed that all activators of the inflammasome NLRP3/NALP3 induce the simultaneous secretion of IL-1alpha and IL-1beta. Although most activators fully rely on the inflammasome for IL-1alpha secretion, some induce the processing and secretion of IL-1alpha in an inflammasome-independent manner.
    UniProt
    P01582
    途径
    NF-kappaB Signaling, Autophagy, Cancer Immune Checkpoints
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