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NAMPT 抗体 (AA 40-56)

This 兔 多克隆 antibody specifically detects NAMPT in IHC 和 ELISA. It exhibits reactivity toward 人.
产品编号 ABIN1169023
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for NAMPT 抗体 (AA 40-56) (ABIN1169023)

抗原

See all NAMPT 抗体
NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))

适用

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宿主

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克隆类型

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多克隆

标记

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This NAMPT antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), ELISA
  • 抗原表位

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    AA 40-56

    原理

    anti-Nampt (Visfatin/PBEF) (human), pAb (NT)

    特异性

    Recognizes human Nampt.

    交叉反应 (详细)

    Weakly cross-reacts with mouse Nampt.

    产品特性

    Polyclonal Antibody. Recognizes human Nampt. Weakly cross-reacts with mouse Nampt. Detects a band of ~54 kDa by Western blot. Source: Rabbit. Applications: ELISA, IHC. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. Nicotinamide phosphoribosyltransferase (Nampt, pre-B cell colony-enhancing factor, PBEF, Visfatin) is an 52 kDa adipokine secreted by adipose tissue and involved in the biosynthesis of nicotinamide adenine dinucleotide (NAD+). Two forms of Nampt exist, an intracellular form (iNampt) and an extracellular form (eNampt). While the function of iNampt as an essential and rate-limiting NAD+ biosynthetic enzyme is well established, the physiological role of eNampt is still a matter of debate. Nampt has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.

    过滤

    0.2 μm filtered

    免疫原

    Synthetic peptide corresponding to aa 40-56 (R40EKKTENSKLRKVKYEE56) of human Nampt (Visfatin/PBEF).
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    0.2μm-filtered solution in PBS, pH 7.4.

    储存液

    Without preservative

    注意事项

    After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.

    储存条件

    4 °C,-20 °C

    储存方法

    +4°C

    -20°C

    Stable for at least 6 months after receipt when stored at -20°C.

    有效期

    6 months
  • 抗原

    NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))

    别名

    Nampt (Visfatin/PBEF)

    背景

    Alternate Names/Synonyms: Pre-B Cell Colony Enhancing Factor 1, PBEF1, Nicotinamide Phosphoribosyltransferase

    Product Description: Nicotinamide phosphoribosyltransferase (Nampt, pre-B cell colony-enhancing factor, PBEF, Visfatin) is an 52 kDa adipokine secreted by adipose tissue and involved in the biosynthesis of nicotinamide adenine dinucleotide (NAD+). Two forms of Nampt exist, an intracellular form (iNampt) and an extracellular form (eNampt). While the function of iNampt as an essential and rate-limiting NAD+ biosynthetic enzyme is well established, the physiological role of eNampt is still a matter of debate. Nampt has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.

    UniProt

    P43490
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