Osteoprotegerin 抗体
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- 抗原 See all Osteoprotegerin (TNFRSF11B) 抗体
- Osteoprotegerin (TNFRSF11B) (Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Osteoprotegerin antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- 特异性
- Recognizes Human Osteoprotegerin (hOPG). Other species not tested.
- 纯化方法
- Affinity Chromatography employing immobilized hOPG matrix
- 免疫原
- Highly purified (>98%) E. Coli derived recombinant Human OPG. Remarks: Molecular Weight: 150 kDa
- Top Product
- Discover our top product TNFRSF11B Primary Antibody
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anti-Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) (AA 22-280) antibody
TNFRSF11B 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) (AA 1-196) antibodyTNFRSF11B 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) (AA 22-281) antibodyTNFRSF11B 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) antibodyTNFRSF11B 适用: 人 WB, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 5G2 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) (AA 243-271) antibodyTNFRSF11B 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) antibodyTNFRSF11B 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) (Internal Region) antibodyTNFRSF11B 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) antibodyTNFRSF11B 适用: 人 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 5A11 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) (AA 1-196) antibodyTNFRSF11B 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) (AA 1-401) antibodyTNFRSF11B 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Sandwich ELISA: To detect Human OPG by Sandwich ELISA (using 100 μL/well antibodysolution) a concentration of 0.5-2.0 μg/mL of this antibody is required. This antigen affinitypurified antibody, in conjunction with Biotinylated anti-Human OPG antibody (PP1107B1 orPP1107B2) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well ofrecombinant Human OPG. Western Blot To detect Human OPG by Western Blot analysis this antibody can be used at aconcentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagentsthe detection limit for recombinant Human OPG is 1.5-3.0 ng/lane, under either reducing ornon-reducing conditions. Immunohistochemistry: This antibody stained Formalin-Fixed Paraffin-Embedded Sectionsof Human breast invasive ductal carcinoma. Use at 0.5 μg/mL with overnight incubation at 4 °C. An HRP-labeled polymer detectionsystem was used with a DAB chromogen. Heat induced antigen retrieval with a pH 6.0Sodium Citrate buffer is recommended.
- 限制
- 仅限研究用
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- 溶解方式
- Restore in sterile water to a concentration of 0.1-1.0 mg/mL.
- 缓冲液
- PBS, pH 7.2 without preservatives
- 储存液
- Without preservative
- 注意事项
- Avoid repeated freezing and thawing. Centrifuge vial prior to opening!
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Prior to reconstitution store at 2-8 °C. Following reconstitution store the antibody at -20 °C.
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- 抗原
- Osteoprotegerin (TNFRSF11B) (Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B))
- 别名
- Osteoprotegerin / TNFRSF11B (TNFRSF11B 产品)
- 别名
- CD254 antibody, ODF antibody, OPGL antibody, OPTB2 antibody, RANKL antibody, TRANCE antibody, hRANKL2 antibody, sOdf antibody, OCIF antibody, OPG antibody, TR1 antibody, Opg antibody, ocif antibody, opg antibody, tr1 antibody, TNF superfamily member 11 antibody, TNF receptor superfamily member 11b antibody, tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) antibody, TNF receptor superfamily member 11B antibody, tumor necrosis factor receptor superfamily member 11b S homeolog antibody, tumor necrosis factor receptor superfamily, member 11b antibody, TNFSF11 antibody, TNFRSF11B antibody, Tnfrsf11b antibody, tnfrsf11b.S antibody
- 物质类
- Chemical
- 背景
- Osteoprotegerin (OPG) is a member of the TNF receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand (TNFSF11/OPGL), both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of the gene have been reported, but their full length nature has not been determined.Synonyms: OCIF, OPG, Osteoclastogenesis inhibitory factor, Tumor necrosis factor receptor superfamily member 11B
- 基因ID
- 4982
- NCBI登录号
- NP_002537
- UniProt
- O00300
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