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CXCL2 抗体

CXCL2 适用: 小鼠 WB, Func, EIA, Neut 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN116268
发货至: 中国
  • 抗原 See all CXCL2 抗体
    CXCL2 (Chemokine (C-X-C Motif) Ligand 2 (CXCL2))
    适用
    • 22
    • 10
    • 9
    • 2
    小鼠
    宿主
    • 34
    • 5
    • 1
    • 1
    克隆类型
    • 35
    • 6
    多克隆
    标记
    • 28
    • 9
    • 3
    • 1
    This CXCL2 antibody is un-conjugated
    应用范围
    • 36
    • 20
    • 9
    • 7
    • 7
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    Western Blotting (WB), Functional Studies (Func), Enzyme Immunoassay (EIA), Neutralization (Neut)
    特异性
    This antibody detects Mouse MIP-2. Other species not tested.
    纯化方法
    Affinity Chromatography employing immobilized murine mMIP-2 matrix
    免疫原
    Highly pure (> 98%) E.coli derived recombinant Murine MIP-2
    Top Product
    Discover our top product CXCL2 Primary Antibody
  • 应用备注
    Neutralisation: To yield one-half maximal inhibition [ND50] of the biological activity of mMIP-2 (15.00 ng/mL), a concentration of 0.52-0.90 μg/mL of this antibody is required. ELISA: Indirect: Using 100 μL/well antibody solution, a concentration of 0.5 - 2.0 μg/mL isrequired. In conjunction with compatible secondary reagents, it allows the detection of atleast 0.2 - 0.4 ng/well of recombinant mMIP-2. Sandwich: Using 100 μL/well antibody solution, a concentration of 0.5 - 2.0 μg/mL isrequired. In conjunction with Biotinylated Anti-Murine MIP-2 (PP1082B) as a detectionantibody, it allows the detection of at least 0.2 - 0.4 ng/well of recombinant mMIP-2. Western Blot: 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagents thedetection limit for recombinant mMIP-2 is 1.5-3.0 ng/lane, under either reducing ornon-reducing conditions.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 溶解方式
    Centrifuge vial prior to opening. Restore in sterile water to a concentration of 0.1-1.0 mg/mL.
    缓冲液
    PBS, pH 7.2
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Prior to reconstitution store at 2-8 °C. Following reconstitution store (in aliquots) at -20 °C.
  • 抗原
    CXCL2 (Chemokine (C-X-C Motif) Ligand 2 (CXCL2))
    别名
    CXCL2 / MIP2A (CXCL2 产品)
    别名
    CINC-2a antibody, GRO2 antibody, GROb antibody, MGSA-b antibody, MIP-2a antibody, MIP2 antibody, MIP2A antibody, SCYB2 antibody, GRO3 antibody, Gro2 antibody, MIP-2 antibody, Mgsa-b antibody, Mip2 antibody, Scyb antibody, Scyb2 antibody, Mip-2 antibody, GROB antibody, MIP-2alpha antibody, C-X-C motif chemokine ligand 2 antibody, chemokine (C-X-C motif) ligand 2 antibody, CXCL2 antibody, Cxcl2 antibody
    背景
    GRO beta is a member of the CXC, or chemokine class. It contains the ELR domain immediately preceding the first cysteine residue near the amino terminus. Other chemokines in this group include IL8, GRO alpha/beta/gamma, mouse KC, ENA78, GCP2, PBP/CTAPIII/beta TG/NAP2. These chemokines act primarily on neutrophils as chemoattractants and activators, including neutrophil degradation with release of myloperoxidase and other enzymes. GRO beta was originally identified as a heparin-binding protein secreted from a murine macrophage cell line in response to endotoxin stimulation. GRO beta is an approximately 8 kDa polypeptide of 73 amino acids. The precursor form of GRO beta consists of 100 amino acids. To generate the mature GRO beta, the precursor cleaves its amino terminal 27 amino acids. GRO beta shows 60 % amino acid homology to human GRO alpha and GRO gamma.Synonyms: C-X-C motif chemokine 2, GRO2, GROB, Gro-beta, Growth-regulated protein beta, MIP-2A, MIP2-alpha, Macrophage inflammatory protein 2-alpha, SCYB2
    基因ID
    20310
    NCBI登录号
    NP_033166
    UniProt
    P10889
    途径
    Cellular Response to Molecule of Bacterial Origin
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