HGF 抗体
Our Local Distributor
北京 101111
Quick Overview for HGF 抗体 (ABIN115703)
抗原
See all HGF 抗体适用
宿主
克隆类型
标记
应用范围
-
-
特异性
- The antibody recognizes human HGF. Other species not tested.
-
纯化方法
- Protein A chromatography
-
免疫原
- Recombinant human HGF
-
-
anti-Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF) (AA 1-728) antibody
HGF 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF) (N-Term) antibodyHGF 适用: 人, 大鼠, 小鼠, 犬, 绵羊, 兔, Cow, 马, 豚鼠, Pig, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF) (AA 521-554) antibodyHGF 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF) (AA 201-300) antibodyHGF 适用: 人, 大鼠, 小鼠, 绵羊 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF) (AA 482-710) antibodyHGF 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF) (AA 306-471) antibodyHGF 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF) (AA 216-265) antibodyHGF 适用: 人, 大鼠, 小鼠, 犬, 兔, Cow, 马, 豚鼠, Hamster, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF) (AA 521-554), (C-Term) antibodyHGF 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB09924 unconjugated
anti-Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF) (AA 495-728) antibodyHGF 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF) (AA 619-728) antibodyHGF 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
-
-
应用备注
-
ELISA: 1-15 μg/mL. Western blot: 1-2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
溶解方式
- Restore in sterile water / PBS to a concentration of > 0.5 mg/mL.
-
缓冲液
- PBS, pH 7.4, without preservative or stabilizer
-
储存液
- Without preservative
-
注意事项
- Avoid repeated freezing and thawing. When reconstituted to a concentration of > 0.5 mg/ml the antibody is stable for six weeks at 2-8°C.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- The lyophilized antibody can be stored at 2-8 °C for up to one month and at -20 °C for one year from despatch.
-
有效期
- 12 months
-
-
- HGF (Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF))
-
别名
- Hepatocyte Growth Factor / HGF
-
背景
- Human Hepatocyte Growth Factor (HGF), also known as scatter factor, is a pleiotrophic cytokine that shows homology to the enzymes of the blood coagulation cascade. It stimulates the motility and invasion of several cancer cell types and can induce angiogenesis. Recently HGF was found to be identical to scatter factor, a fibroblast-derived factor promoting the dissociation of epithelial and vascular endothelial cell colonies in monolayer cell cultures by stimulating cell migration. HGF is synthesized as a biologically inactive single chain precursor, which is cleaved by a specific, extracellular serum serine protease to a fully active heterodimer. This mature, biologically active HGF consists of a disulfide-linked alpha-beta heterodimer of the two cleavage products. Previous studies have shown that single chain and heterodimeric HGF are equally active in in vitro assay systems due to either production of the serine protease in cell culture or the presence of the ubiquitious protease in serum. All biological responses induced by HGF are elicited by binding to its transmembrane tyrosine kinase receptor, which is encoded by the MET proto-oncogene. After autophosphorylation of the receptor different cytoplasmatic effectors are activated that bind to the same multifunctional docking site of the receptor. HGF function is essential for normal development. Hepatocytes have to be primed before they can fully respond to HGF. This priming requires cytokines as TNF and IL-6. Recent studies have suggested that HGF synergizes with basic FGF in the induction of angiogenesis.Synonyms: HPTA, Hepatopoeitin-A, Scatter factor
-
基因ID
- 3082
-
NCBI登录号
- NP_000592
-
UniProt
- P14210
-
途径
- RTK signaling, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor
抗原
-
