The basic IGF-1-like forms (pI>9.0) showed substantial cross-reactivity, as did Rat and Mouse sera. Monoclonal antibody BM23 was capable of abolishing the biological activities of IGF-1 in-vitro bioassays for insulin-like, mitogenic and sulphation activities. Cross-reactivity: ILGF-1:100 % ILGF-2:1 % Proinsulin: 1.4 % MSF: 1 % Insulin: < 0.1 %.Aff. Const.:10e8-10e9 l/mole
RIA. ELISA. Immunohistochemistry on Frozen Sections. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
限制
仅限研究用
浓度
1.0 mg/mL
缓冲液
PBS buffer with 0.09 % Sodium Azide as preservative.
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Avoid repeated freezing and thawing.
储存条件
4 °C/-20 °C
储存方法
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Insulin is a pancreatic hormone that regulates glucose uptake and the synthesis of protein and fat. The insulin like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth promoting activity. IGF1 (Insulin Like Growth Factor I) is a polypeptide growth factor, which stimulates the proliferation of a wide range of cell types including muscle, bone, and cartilage tissue. IGF1 functions as an autocrine regulator of growth.Synonyms: IBP1, IGF-I, MGF, Mechano growth factor, Somatomedin-C