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Phospholamban 抗体 (N-Term)

PLN 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1109616
发货至: 中国
  • 抗原 See all Phospholamban (PLN) 抗体
    Phospholamban (PLN)
    抗原表位
    • 30
    • 18
    • 17
    • 9
    • 8
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 84
    • 24
    • 23
    • 3
    • 2
    • 2
    • 2
    人, 大鼠, 小鼠
    宿主
    • 84
    • 1
    • 1
    克隆类型
    • 84
    • 2
    多克隆
    标记
    • 33
    • 6
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This Phospholamban antibody is un-conjugated
    应用范围
    • 32
    • 26
    • 26
    • 26
    • 13
    • 10
    • 9
    • 8
    • 7
    • 6
    • 6
    • 4
    • 1
    Western Blotting (WB)
    特异性
    This antibody detects Phospholamban (N-term). No cross reactivity with other proteins.
    交叉反应 (详细)
    Species reactivity (tested):Human, rat, mouse.
    纯化方法
    Immunogen affinity purified
    免疫原
    A synthetic peptide corresponding to a sequence at the N-terminal of human Phospholamban .Remarks: Sequence is identical to the related rat and mouse sequence.
    亚型
    IgG
    Top Product
    Discover our top product PLN Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 溶解方式
    0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    缓冲液
    5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3
    储存液
    Sodium azide, Thimerosal (Merthiolate)
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    Phospholamban (PLN)
    别名
    Phospholamban (PLN 产品)
    别名
    LOC100226261 antibody, plb antibody, cmd1p antibody, CMD1P antibody, CMH18 antibody, PLB antibody, Plb antibody, Plm antibody, phospholamban antibody, PLN antibody, pln antibody, Pln antibody
    背景
    Phospholamban is a 52 amino acid integral membrane protein that regulates the Ca2+ pump in cardiac muscle and skeletal muscle cells. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the inotropic response elicited in heart by beta-agonists. Phospholamban is also expressed in slow-twitch skeletal muscle and some smooth muscle cells. McTiernan et al. (1999) observed that human ventricle and quadriceps displayed high levels of phospholamban transcripts and proteins, with markedly lower expression observed in smooth muscles, while the right atrium also expressed low levels of phospholamban. The structure of the human phospholamban gene closely resembles that reported for chicken, rabbit, rat, and mouse. Comparison of the human to other mammalian phospholamban genes indicated a marked conservation of sequence for at least 217 bp upstream of the transcription start site.Synonyms: Cardiac phospholamban, PLB, PLN
    基因ID
    5350
    NCBI登录号
    NP_002658
    UniProt
    P26678
    途径
    Negative Regulation of Transporter Activity
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