TNF alpha 抗体
Our Local Distributor
北京 101111
Quick Overview for TNF alpha 抗体 (ABIN1109399)
抗原
See all TNF alpha 抗体适用
宿主
克隆类型
标记
应用范围
-
-
特异性
- The antibody reacts with natural and recombinant TNF-alpha and recognizes membrane and receptor bound TNF-alpha. The antibody shows Neutralizing activity.
-
交叉反应 (详细)
- Species reactivity (tested):Mouse, Rat.
-
纯化方法
- Protein A Chromatography
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
浓度
- 0.1 mg/mL
-
缓冲液
- PBS, 0.1 % BSA
-
储存条件
- 4 °C
-
储存方法
- Store undiluted at 2-8 °C.
-
-
- TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))
-
别名
- Tumor Necrosis Factor (TNF-Alpha)
-
背景
- Tumor Necrosis Factor alpha (TNF-alpha) is a cytokine which has diverse immunomodulatory, anti-tumor and toxic effects. TNF-alpha has been detected in diverse inflammatory status and appears to be a critical mediator in the lethality of septic shock. Furthermore, TNF-alpha has also been found in inflammatory foci such as synovial effusions in rheumatoid arthritis, systemic circulation in septic shock, parasitemia and rejection of renal transplants.Synonyms: Cachectin, TNF, TNF-a, TNFA, TNFSF2, Tumor necrosis factor ligand superfamily member 2
-
基因ID
- 21926
-
NCBI登录号
- NP_038721
-
UniProt
- P06804
-
途径
- NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, TLR signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome
抗原
-