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SERPINB9 抗体

SERPINB9 适用: 小鼠 WB, FACS 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1109125
发货至: 中国
  • 抗原 See all SERPINB9 抗体
    SERPINB9 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 9 (SERPINB9))
    适用
    • 37
    • 9
    • 8
    • 1
    • 1
    小鼠
    宿主
    • 31
    • 7
    • 1
    克隆类型
    • 33
    • 6
    多克隆
    标记
    • 27
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SERPINB9 antibody is un-conjugated
    应用范围
    • 29
    • 16
    • 11
    • 5
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    特异性
    The antibody recognizes Mouse Spi-6, also known as Serpin B9, a cytoplasmic serine protease inhibitor of ~42 kDa. It shows no crossreactivity with Mouse proteins related to Spi-6.
    交叉反应 (详细)
    Species reactivity (tested):Mouse.
    纯化方法
    Protein A Chromatography
    免疫原
    Recombinant GST-Spi-6
    亚型
    Ig Fraction
    Top Product
    Discover our top product SERPINB9 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.1 mg/mL
    缓冲液
    PBS, 0.02 % Sodium Azide, 0.1 % BSA
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store undiluted at 2-8 °C.
  • 抗原
    SERPINB9 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 9 (SERPINB9))
    别名
    Spi-6 (SERPINB9 产品)
    别名
    SERPINB9 antibody, BB283241 antibody, CAP-3 antibody, CAP3 antibody, PI-9 antibody, PI9 antibody, Spi6 antibody, ovalbumin antibody, serpin family B member 9 antibody, serpin peptidase inhibitor, clade B (ovalbumin), member 9 antibody, serine (or cysteine) peptidase inhibitor, clade B, member 9 antibody, Serpinb9 antibody, SERPINB9 antibody
    背景
    Spi-6 is expressed in dendritic cells, lymphocytes and specific cell types at immune-privileged sites. It inactivates granzyme B, a natural occurring inducer of programmed cell death. As such, Spi-6 functions as anti-apoptotic protein. In cytotxic T cells (CTL), Spi-6 is required to protect clonal bursts (expansion) from granzyme B induced cell death. However, it is not required for the development of memory cells. Expression of SPI-6 is of crucial importance in the escape of several tumors from a CTL response and is, therefore, a parameter that influences the feasibility of CTL-mediated immunotherapy of cancer.Synonyms: Cytoplasmic antiproteinase 3, PI-9, serpin B9
    基因ID
    20723
    NCBI登录号
    NP_033282
    UniProt
    O08797
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