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SNAP25 抗体 (C-Term)

SNAP25 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1109085
发货至: 中国
  • 抗原 See all SNAP25 抗体
    SNAP25 (Synaptosomal-Associated Protein, 25kDa (SNAP25))
    抗原表位
    • 15
    • 15
    • 8
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    • 3
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    • 1
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    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 89
    • 62
    • 60
    • 8
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    • 2
    • 1
    • 1
    • 1
    • 1
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    • 1
    人, 大鼠, 小鼠
    宿主
    • 92
    • 18
    • 4
    • 4
    • 1
    克隆类型
    • 93
    • 23
    • 1
    多克隆
    标记
    • 65
    • 8
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    • 4
    • 4
    • 4
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    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
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    This SNAP25 antibody is un-conjugated
    应用范围
    • 85
    • 46
    • 27
    • 15
    • 13
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    • 13
    • 13
    • 12
    • 8
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    • 5
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    Western Blotting (WB)
    特异性
    This antibody detects SNAP25 (C-term). No cross reactivity with other proteins.
    交叉反应 (详细)
    Species reactivity (tested):Human, Mouse, rat
    纯化方法
    Immunogen affinity purified
    免疫原
    A synthetic peptide corresponding to a sequence at the C-terminal of human SNAP25 .Remarks: The sequence is identical to the related rat and mouse sequence.
    亚型
    IgG
    Top Product
    Discover our top product SNAP25 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 溶解方式
    0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    缓冲液
    5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3
    储存液
    Sodium azide, Thimerosal (Merthiolate)
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    SNAP25 (Synaptosomal-Associated Protein, 25kDa (SNAP25))
    别名
    SNAP25 (SNAP25 产品)
    别名
    RIC-4 antibody, RIC4 antibody, SEC9 antibody, SNAP antibody, SNAP-25 antibody, bA416N4.2 antibody, dJ1068F16.2 antibody, SNAP-25B antibody, SNAP-25a antibody, ric-4 antibody, ric4 antibody, sec9 antibody, snap-25 antibody, Bdr antibody, sp antibody, fj55h11 antibody, snap25 antibody, wu:fj55h11 antibody, Snap antibody, snap25.2 antibody, wu:fj33h05 antibody, synaptosome associated protein 25 antibody, synaptosome associated protein 25kDa S homeolog antibody, synaptosomal-associated protein, 25kDa antibody, synaptosomal-associated protein 25 antibody, synaptosome associated protein 25kDa antibody, synaptosome associated protein 25kDa L homeolog antibody, zgc:101731 antibody, synaptosomal-associated protein, 25b antibody, SNAP25 antibody, Snap25 antibody, snap25.S antibody, snap25 antibody, BACOIKO003_07 antibody, Tsp_10811 antibody, snap25.L antibody, zgc:101731 antibody, snap25b antibody
    背景
    Synaptosome-associated protein of 25,000 daltons also known as SNAP-25 is a protein which in humans encodes a 25-kD protein of 206 amino acids. It was first investigated as a neuron-specific gene preferentially expressed in mouse hippocampus. The tSNARE (the target-membrane soluble NSFattachment protein receptor, where NSF is N-ethylmaleimide-sensitive fusion protein) synaptosomalassociated protein of 25 kDa (SNAP-25) is expressed in pancreatic B-cells and its cleavage by botulinum neurotoxin E (BoNT/E) abolishes stimulated secretion of insulin. In the nervous system, two SNAP-25 isoforms (a and b) have been described, which are produced by alternative splicing. Nagy et al. (2004) identified mammalian Snap25a and Snap25b as targets of protein kinase A, a key regulator of neurosecretion that primes slowly releasable pools and readily releasable pools of secretory vesicles. SNAP-25 inhibits P/Q-and L-type voltage-gated calcium channels located presynaptically and interacts with the synaptotagmin C2B domain in Ca2+-independent fashion. In glutamatergic synapses SNAP-25 decreases the Ca2+ responsiveness, while it is naturally absent in GABAergic synapses.Synonyms: RIC4, SNAP, SNAP-25, SUP, Super Protein, Synaptosomal-associated 25 kDa protein, Synaptosomal-associated protein 25, ric-4
    基因ID
    6616
    NCBI登录号
    NP_003072
    UniProt
    P60880
    途径
    Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
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