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SMAD1 抗体 (C-Term)
SMAD1
适用: 人, 大鼠
WB
宿主: 兔
Polyclonal
unconjugated
SMAD1抗体详情
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抗原
See all SMAD1 抗体
SMAD1
(SMAD, Mothers Against DPP Homolog 1 (SMAD1))
抗原表位
All epitopes for SMAD1 抗体
AA 442-456, C-Term
适用
All reactivities for SMAD1 抗体
人, 大鼠
宿主
All hosts for SMAD1 抗体
兔
克隆类型
All clonalities for SMAD1 抗体
多克隆
标记
All conjugates for SMAD1 抗体
This SMAD1 antibody is un-conjugated
应用范围
All applications for SMAD1 抗体
Western Blotting (WB)
特异性
This antibody detects SMAD1/2/3/5 (C-term, 442-456). No cross reactivity with other proteins.
交叉反应 (详细)
Species reactivity (tested):Human, rat
纯化方法
Immunogen affinity purified
免疫原
A synthetic peptide corresponding to a sequence at the C-terminal of human Smad 1,2,3,5 (442-456aa), identical to the related rat sequence
亚型
IgG
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Discover our top product SMAD1 Primary Antibody
Alternatives
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使用细节
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应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
贮存及处理
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溶解方式
0.2 mL of distilled water will yield a concentration of 500 μg/mL.
缓冲液
5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3
储存液
Sodium azide, Thimerosal (Merthiolate)
注意事项
This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
注意事项
Avoid repeated freezing and thawing.
储存条件
4 °C/-20 °C
储存方法
Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
SMAD1目标详情
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抗原
SMAD1
(SMAD, Mothers Against DPP Homolog 1 (SMAD1))
别名
SMAD1 (SMAD1 产品 )
别名
MLP antibody, Xmad1 antibody, Xsmad1 antibody, bsp1 antibody, jv4-1 antibody, jv41 antibody, madh1 antibody, madr1 antibody, smad-1 antibody, MADH1 antibody, fb39h09 antibody, wu:fb39h09 antibody, wu:fb97e04 antibody, 2/23 antibody, CG12399 antibody, Dmel\\CG12399 antibody, E(zen)2 antibody, En(vvl) antibody, MAD antibody, Mat antibody, P-Mad antibody, P-mad antibody, PMad antibody, Smad antibody, Smad1 antibody, apg antibody, c28 antibody, dMAD antibody, dMad antibody, l(2)K00237 antibody, l(2)k00237 antibody, mad antibody, p-Mad antibody, pMAD antibody, pMad antibody, pSmad antibody, BSP-1 antibody, BSP1 antibody, JV4-1 antibody, JV41 antibody, MADR1 antibody, AI528653 antibody, Madh1 antibody, Madr1 antibody, Mlp1 antibody, MusMLP antibody, smad1 antibody, xmad antibody, SMAD family member 1 antibody, Mothers against dpp antibody, SMAD family member 1 L homeolog antibody, smad1 antibody, SMAD1 antibody, Mad antibody, Smad1 antibody, smad1.L antibody
背景
SMADs are proteins that modulate the activity of transforming growth factor beta ligands. The SMADs,often in complex with other SMADs/CoSMAD, act as transcription factors that regulate the expression of certain genes. Zhu, H et al concluded that targeted ubiquitination of SMADs may serve to control both embryonic development and a wide variety of cellular responses to TGF-beta signals. R-Smads or receptor regulated Smads are a class of proteins that include SMAD1, SMAD2, SMAD3, SMAD5, and SMAD8. In response to signals by the TGF-β superfamily of ligands these proteins associate with receptor kinases and are phosphorylated at an SSXS motif at their extreme C-terminus. These proteins then typically bind to the common mediator Smad or co-SMAD SMAD4.Synonyms: 2, 3, 5, SMAD1, SMAD2, SMAD3, SMAD5
基因ID
4086
NCBI登录号
NP_001003688
UniProt
Q15797
途径
Stem Cell Maintenance , Regulation of Muscle Cell Differentiation , Skeletal Muscle Fiber Development
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