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RUNX2 抗体 (C-Term)

This anti-RUNX2 antibody is a 兔 多克隆 antibody detecting RUNX2 in WB 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN1108916
发货至: 中国

Quick Overview for RUNX2 抗体 (C-Term) (ABIN1108916)

抗原

See all RUNX2 抗体
RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))

适用

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人, 小鼠, 大鼠

宿主

  • 122
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克隆类型

  • 113
  • 25
多克隆

标记

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This RUNX2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    C-Term

    特异性

    This antibody detects RUNX2 (C-term). No cross reactivity with other proteins.

    交叉反应 (详细)

    Species reactivity (tested):Human, mouse, rat.

    纯化方法

    Immunogen affinity purified

    免疫原

    Synthetic peptide corresponding to a sequence at the C-terminal of human CBFA1 .Remarks: Sequence is identical to the related rat and mouse sequence.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 溶解方式

    0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    缓冲液

    5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3

    储存液

    Sodium azide, Thimerosal (Merthiolate)

    注意事项

    This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))

    别名

    RUNX2

    背景

    Core binding factor A1 (CBFA1/RUNX2) is a runt-like transcription factor essential for osteoblast differentiation. This protein is a member of the RUNX family of transcription factors and has a Runt DNA-binding domain. It is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. D'Souza et al.(1999) indicate a non-redundant role for Cbfa1 in tooth development that may be distinct from that in bone formation. In odontogenesis, Cbfa1 is not involved in the early signaling networks regulating tooth initiation and early morphogenesis but regulates key epithelial-mesenchymal interactions that control advancing morphogenesis and histodifferentiation of the epithelial enamel organ.Synonyms: AML-3, AML3, Acute myeloid leukemia 3 protein, CBFA1, Core-binding factor subunit alpha-1, OSF-2, OSF2, Osteoblast-specific transcription factor 2, PEA2-alpha A, PEBP2-alpha A, PEBP2A, Polyomavirus enhancer-binding protein 2 alpha A subunit, Runt-related transcription factor 2, SL3-3 enhancer factor 1 alpha A subunit, SL3/AKV core-binding factor alpha A subunit

    基因ID

    860

    NCBI登录号

    NP_001015051

    UniProt

    Q13950
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