PMP22 抗体 (Extracellular Domain, N-Term)
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- 抗原 See all PMP22 抗体
- PMP22 (Peripheral Myelin Protein 22 (PMP22))
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抗原表位
- AA 121-133, Extracellular Domain, N-Term
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适用
- 人, 猕猴
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This PMP22 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- 序列
- CRHPEWHLNS DYSYG
- 特异性
- This antibody recognizes human peripheral myelin protein 22 (PMP22).
- 交叉反应 （详细）
- Species reactivity (tested):Human, rhesus monkey
- 纯化方法
- Protein G
- 免疫原
- Peptide corresponding to amino acids 121-133 in the second extracellular domain of human PMP2 with an extra N-terminal cysteine residue
- 克隆位点
- CF1
- 亚型
- IgG1
- Top Product
- Discover our top product PMP22 Primary Antibody
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anti-Peripheral Myelin Protein 22 (PMP22) (AA 101-160) antibody
PMP22 适用: 大鼠, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Peripheral Myelin Protein 22 (PMP22) (C-Term) antibodyPMP22 适用: 人, 大鼠, 小鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Peripheral Myelin Protein 22 (PMP22) (AA 1-64) antibodyPMP22 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Peripheral Myelin Protein 22 (PMP22) (C-Term) antibodyPMP22 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Peripheral Myelin Protein 22 (PMP22) (AA 31-133) antibodyPMP22 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Peripheral Myelin Protein 22 (PMP22) (AA 31-133) antibodyPMP22 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C10 unconjugated
anti-Peripheral Myelin Protein 22 (PMP22) (AA 32-64) antibodyPMP22 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Peripheral Myelin Protein 22 (PMP22) antibodyPMP22 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Peripheral Myelin Protein 22 (PMP22) (C-Term) antibodyPMP22 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Peripheral Myelin Protein 22 (PMP22) (AA 27-76) antibodyPMP22 适用: 人, Cow, 猴, 豚鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.1 mg/mL
- 缓冲液
- PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store at 2 - 8 °C.
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- 抗原
- PMP22 (Peripheral Myelin Protein 22 (PMP22))
- 别名
- PMP22 (PMP22 产品)
- 别名
- CMT1A antibody, CMT1E antibody, DSS antibody, GAS-3 antibody, HMSNIA antibody, HNPP antibody, Sp110 antibody, 22kDa antibody, Gas-3 antibody, Tr antibody, trembler antibody, pmp22 antibody, wu:fa04d03 antibody, wu:fa08d03 antibody, MGC80653 antibody, PMP22 antibody, MGC69407 antibody, id:ibd2630 antibody, wu:fb81f09 antibody, zgc:136919 antibody, peripheral myelin protein 22 antibody, peripheral myelin protein 22a antibody, peripheral myelin protein 22 S homeolog antibody, peripheral myelin protein 22b antibody, PMP22 antibody, Pmp22 antibody, pmp22a antibody, pmp22.S antibody, pmp22 antibody, pmp22b antibody
- 背景
- PMP22 is a 160 amino acid glycoprotein and contains four hydrophobic domains, presumably transmembrane regions. It is the second most abundant protein in the mammalian nervous system, but is, at least in rodents, also found in other tissues, including the liver and gut. Myelin protein zero (P0) is the most abundant protein in mammalian peripheral nerve myelin. An interaction between P0 and PMP22 has been detected in compact myelin. Defects in PMP22 have been related to Charcot-Marie-Tooth disease (CMT) and inflammatory demyelinating neuropathy (IDP). Immunization with PMP22 induces experimental auto-immune neuritis without central nervous inflammation. Therefore, PMP22 is considered as candidate auto-antigen in inflammatory diseases of the peripheral nervous system, including both acute and chronic inflammatory demyelinating polyradiculoneuropathy.Synonyms: GAS-3, GAS3, Growth arrest-specific protein 3, PMP-22, Peripheral myelin protein 22
- 基因ID
- 5376
- NCBI登录号
- NP_000295
- UniProt
- Q01453
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